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Serostatus

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Serostatus refers to the presence or absence of a serological marker in the blood. The presence of detectable levels of a specific marker within the serum is considered seropositivity, while the absence of such levels is considered seronegativity.

HIV/AIDS

The term serostatus is commonly used in HIV/AIDS prevention efforts. In recent years, social advocacy has emphasized the importance of learning one's HIV/AIDS serostatus in an effort to curtail the spread of the disease.[1]

Autoimmune disease

Researchers have investigated the effects of autoantibody serostatus on autoimmune disease presentation.[2][3][4] Study of seronegative patient populations has led to the identification of additional autoantibodies that could potentially help with diagnosis.[5][6]

See also

References

  1. ^ Janssen, Robert S.; Holtgrave, David R.; Valdiserri, Ronald O.; et al. (July 2001). "The Serostatus Approach to Fighting the HIV Epidemic: prevention strategies for infected individuals". American Journal of Public Health. 91 (7). American Public Health Association: 1019–1024. doi:10.2105/AJPH.91.7.1019. ISSN 1541-0048. PMC 1446705. PMID 11441723. {{cite journal}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)
  2. ^ Jarius, Sven; Ruprecht, Klemens; Wildemann, Brigitte; et al. (January 2012). "Contrasting disease patterns in seropositive and seronegative neuromyelitis optica: A multicentre study of 175 patients". Journal of Neuroinflammation. 9 (1). BioMed Central: 14. doi:10.1186/1742-2094-9-14. PMC 3283476. PMID 22260418. {{cite journal}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)CS1 maint: unflagged free DOI (link)
  3. ^ Ajeganova, Sofia; Huizinga, Tom W J (November 2014). "Rheumatoid arthritis: Seronegative and seropositive RA: alike but different?". Nature Reviews Rheumatology. 11 (1). Nature Publishing Group: 8–9. doi:10.1038/nrrheum.2014.194. ISSN 1759-4804. PMID 25403158. {{cite journal}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)
  4. ^ Balasubramanian, Gokulakrishnan; Sugumar, Aravind; Smyrk, Thomas C; et al. (2012). "Demystifying seronegative autoimmune pancreatitis". Pancreatology. 12 (4). Elsevier: 289–294. doi:10.1016/j.pan.2012.05.003. PMID 22898628. {{cite journal}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)
  5. ^ Somers, Klaartje; Geusens, Piet; Elewaut, Dirk; et al. (February 2011). "Novel autoantibody markers for early and seronegative rheumatoid arthritis". Journal of Autoimmunity. 36 (1). Elsevier: 33–46. doi:10.1016/j.jaut.2010.10.003. ISSN 0896-8411. PMID 21071175. {{cite journal}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)
  6. ^ Pevzner, Alexandra; Schoser, Benedikt; Peters, Katja; et al. (August 2011). "Anti-LRP4 autoantibodies in AChR- and MuSK-antibody-negative myasthenia gravis" (PDF). Journal of Neurology. 259 (3). Springer-Verlag: 427–435. doi:10.1007/s00415-011-6194-7. ISSN 1432-1459. PMID 21814823. {{cite journal}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)