Non-invasive cerebellar stimulation

Non-invasive cerebellar stimulation is the application of non-invasive neurostimulation techniques on the cerebellum to modify its electrical activity. Techniques such as transcranial magnetic stimulation (TMS) or transcranial direct current stimulation (tDCS) can be used^[1]. The cerebellum is a high potential target for neuromodulation of neurological and psychiatric disorders due to the high density of neurons in its superficial layer, its electrical properties, and its participation in numerous closed-loop circuits involved in motor, cognitive, and emotional functions.^[2]

Cerebellar TMS is a relatively new field that is undergoing experimental research. There is not yet sufficient evidence of the therapeutic effects of cerebellar TMS,^[3] although some successful results have been reported in other clinical studies of TMS used to treat the frontal lobe.^[4]

References

^ Grimaldi, G.; Argyropoulos, G. P.; Boehringer, A.; Celnik, P.; Edwards, M. J.; Ferrucci, R.; Galea, J. M.; Groiss, S. J.; Hiraoka, K. (February 2014). "Non-invasive cerebellar stimulation--a consensus paper" (PDF). Cerebellum (London, England). 13 (1): 121–138. doi:10.1007/s12311-013-0514-7. ISSN 1473-4230. PMID 23943521.
^ van Dun, Kim; Manto, Mario (27 December 2017). "Non-invasive Cerebellar Stimulation: Moving Towards Clinical Applications for Cerebellar and Extra-Cerebellar Disorders". The Cerebellum. 17 (3): 259–263. doi:10.1007/s12311-017-0908-z. ISSN 1473-4222. PMID 29282616.
^ Minks, Eduard; Kopickova, Marie; Marecek, Radek; Streitova, Hana; Bares, Martin (June 2010). "Transcranial magnetic stimulation of the cerebellum". Biomedical Papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia. 154 (2): 133–139. doi:10.5507/bp.2010.020. ISSN 1213-8118. PMID 20668494.
^ Derstine T, Lanocha K, Wahlstrom C, Hutton TM (November 2010). "Transcranial magnetic stimulation for major depressive disorder: a pragmatic approach to implementing TMS in a clinical practice". Ann Clin Psychiatry. 22 (4 Suppl): S4–11. PMID 21180663.

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[1] Grimaldi, G.; Argyropoulos, G. P.; Boehringer, A.; Celnik, P.; Edwards, M. J.; Ferrucci, R.; Galea, J. M.; Groiss, S. J.; Hiraoka, K. (February 2014). "Non-invasive cerebellar stimulation--a consensus paper" (PDF). Cerebellum (London, England). 13 (1): 121–138. doi:10.1007/s12311-013-0514-7. ISSN 1473-4230. PMID 23943521.

[2] van Dun, Kim; Manto, Mario (27 December 2017). "Non-invasive Cerebellar Stimulation: Moving Towards Clinical Applications for Cerebellar and Extra-Cerebellar Disorders". The Cerebellum. 17 (3): 259–263. doi:10.1007/s12311-017-0908-z. ISSN 1473-4222. PMID 29282616.

[3] Minks, Eduard; Kopickova, Marie; Marecek, Radek; Streitova, Hana; Bares, Martin (June 2010). "Transcranial magnetic stimulation of the cerebellum". Biomedical Papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia. 154 (2): 133–139. doi:10.5507/bp.2010.020. ISSN 1213-8118. PMID 20668494.

[4] Derstine T, Lanocha K, Wahlstrom C, Hutton TM (November 2010). "Transcranial magnetic stimulation for major depressive disorder: a pragmatic approach to implementing TMS in a clinical practice". Ann Clin Psychiatry. 22 (4 Suppl): S4–11. PMID 21180663.

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See also

References