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Debbie C. Crans

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Debbie C. Crans
Debbie Crans after receiving her 2015 Cope Scholar Award
Born (1955-08-13) August 13, 1955 (age 69)[1]
Academic background
Doctoral advisorGeorge M. Whitesides
Academic work
Institutions
Websitehttp://www.chem.colostate.edu/people/crans/

Debbie C. Crans is a professor of chemistry at Colorado State University,[2] specializing in fundamental chemistry and biochemistry of drugs with particular interest in vanadium and other transition metal ions as metals in medicine and their mechanisms of toxicity.[1] She currently resides in Northern Colorado with her husband and three daughters. One daughter is pursuing the PhD in chemistry at Northwestern University, one is an undergraduate student at Colorado State University, and one works as a financial planner.

Education

Debbie Crans studied at the University of Copenhagen, studying for her Cand. Scient. 1. part (BS) in 1974–1978, then her Cand. Scient. 2. part (research) in 1978–1980. She then moved to Harvard University in the US to work under George M. Whitesides, and she successfully defended her PhD dissertation on "Methodology in Enzyme-Catalyzed Organic Synthesis: Glycerol Kinase Catalyzed Phosphorylations". She went on to do postdoctoral work with Orville L. Chapman and Paul D. Boyer at the University of California, Los Angeles from 1985–1986, studying "Mechanistic Enzymology on F1-ATP Synthase from Chloroplasts and Beef Heart".[1]

Career

Crans is best known for her work on the role of vanadium in biological systems, especially the effects of its compounds on diabetes. She has worked as senior editor several books on vanadium, such as Vanadium Compounds: Chemistry, Biochemistry, and Therapeutic Applications,[3] Vanadium: The Versatile Metal[4] and Vanadium in Biochemistry.[5] Crans served as chair of the American Chemical Society in 2015 and 2016. She has also been associate editor for The Journal of Chemistry and the Coordination Chemistry Reviews.[6]

Awards

International Awards

2019 ACS award for Distinguished Service in the Advancement of Inorganic Chemistry[7]

2015 Arthur P Cope ACS Scholar award[8]

2012 Lectureship award, Japanese Coordination Chemistry Society[6]

2004 Vanadis award from the International Vanadium Symposium in Szeged[6]

2000 Japan Society of Promotion of Science award[6]

2000 Alexander Humboldt Senior Research awardee[6]

National Awards

2017 ChemLuminary Awards Young Chemists Committee[9]

2016 Royal Society Fellow[6]

2014 AAAS Fellow[10]

2009 ACS Fellow[11]

1993-96 Alfred P Sloan Research Fellow[12]

1994 Alberta Heritage Foundation award[6]

1990-1992 Eli Lilly Young Investigator award[6]

1989-1994 National Institutes of Health FIRST award[6]

Publications and Impact Factor

Crans has contributed to over 215 peer-reviewed articles. As of spring of 2019, her work has been cited 7,200 times excluding self-citations making her h-index of 53. Her review paper, "The chemistry and biochemistry of vanadium and the biological activities exerted by vanadium compounds" has been cited over 900 times.[13] Her study on "Effects of vanadium complexes with organic ligands on glucose metabolism: a comparison study in diabetic rats"[14] describes the use of vanadium compounds as hypoglycemic agents, and it has been widely cited.[15]

References

  1. ^ a b c Crans, Debbie C. "Crans Brief Resume". Retrieved 24 August 2016.
  2. ^ "Debbie Crans". Colorado State University. Retrieved 24 August 2016.
  3. ^ Tracy, Alan S.; Crans, Debbie C., eds. (1998). Vanadium Compounds: Chemistry, Biochemistry, and Therapeutic Applications. ACS Symposium Series. Washington, DC: American Chemical Society.
  4. ^ Kustin, Kenneth; Pessoa, João Costa; Crans, Debbie C., eds. (2007). Vanadium: The Versatile Metal. ACS Symposium Series. Washington, DC: American Chemical Society.
  5. ^ Crans, Debbie C.; Simone, Carmen (2013). Vanadium in Biochemistry. Hoboken, NJ: Wiley.
  6. ^ a b c d e f g h i Crans, Debbie. Circulum Vitae.
  7. ^ "2019 National Award Recipients Citations". American Chemical Society. Retrieved 2019-05-09.
  8. ^ "Arthur C. Cope Scholar Awards". American Chemical Society. Retrieved 2019-05-09.
  9. ^ "2017 ChemLuminary Award Winners". American Chemical Society. Retrieved 2019-05-09.
  10. ^ "Elected Fellows". American Association for the Advancement of Science. Retrieved 2019-05-09.
  11. ^ "ACS Fellows Program". American Chemical Society. Retrieved 2019-05-09.
  12. ^ "Past Fellows". sloan.org. Retrieved 2019-05-09.
  13. ^ Crans, Debbie C (2004). "The chemistry and biochemistry of vanadium and the biological activities exerted by vanadium compounds". Chemical Reviews. 104: 849–902. doi:10.1021/cr020607t.
  14. ^ Crans, Debbie C. (30 May 2000). "Chemistry and insulin-like properties of vanadium(IV) and vanadium(V) compounds". Journal of Inorganic Biochemistry. 80 (1–2): 123–131. doi:10.1016/s0162-0134(00)00048-9. PMID 10885472.
  15. ^ "Chemistry and insulin-like properties of vanadium (IV) and vanadium (V) compounds". Google Scholar. Retrieved 24 August 2016.