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Ced-5

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Cell death abnormality gene 5
Identifiers
OrganismCaenorhabditis elegans
SymbolCED-5
Entrez177942
HomoloGene55575
RefSeq (mRNA)NM_069537.7
RefSeq (Prot)NP_501938.1
UniProtG5EEN3
Other data
ChromosomeIV: 10.48 - 10.49 Mb
Search for
StructuresSwiss-model
DomainsInterPro

CED-5 is an ortholog of the mammalian protein Dock180,which present in the nematode worm C. elegans.[1], the Drosophila melanogaster ortholog of CED-5 is Myoblast city.[2]

Reference

  1. ^ Wu YC, Horvitz HR (April 1998). "C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180". Nature. 392 (6675): 501–4. Bibcode:1998Natur.392..501W. doi:10.1038/33163. PMID 9548255.
  2. ^ Nolan KM, Barrett K, Lu Y, Hu KQ, Vincent S, Settleman J (November 1998). "Myoblast city, the Drosophila homolog of DOCK180/CED-5, is required in a Rac signaling pathway utilized for multiple developmental processes". Genes & Development. 12 (21): 3337–42. doi:10.1101/GAD.12.21.3337. PMC 317223. PMID 9808621.