Seraticin

Seraticin is an antibiotic discovered by scientists at Swansea University able to inhibit 12 different strains of methicillin-resistant Staphylococcus aureus (MRSA), as well as E. coli and C. difficile. The research was funded by the charity Action Medical Research, with support from the Rosetrees Trust. Seraticin was isolated as a compound of less than 500 Da molecular weight from the maggot secretions of the common green bottle fly (Lucilia sericata).^[1]^[2] It was patented in 2010 and has the empirical formula C
₁₀H
₁₆N
₆O
₉, but its chemical identity is unknown.^[3]

References

^ "Multi-Tasking Maggots In Superbug Showdown". ScienceDaily. 11 August 2012. Retrieved 8 December 2012.
^ Bexfield A, Bond AE, Roberts EC, et al. (April 2008). "The antibacterial activity against MRSA strains and other bacteria of a <500 Da fraction from maggot excretions/secretions of Lucilia sericata (Diptera: Calliphoridae)". Microbes Infect. 10 (4): 325–33. doi:10.1016/j.micinf.2007.12.011. PMID 18400544.
^ "(WO2011042684) Antimicrobial Composition and a Method of Controlling Contamination and Infection Using Said Composition". US Patent. October 1, 2010. Retrieved 8 December 2012.

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[1] "Multi-Tasking Maggots In Superbug Showdown". ScienceDaily. 11 August 2012. Retrieved 8 December 2012.

[2] Bexfield A, Bond AE, Roberts EC, et al. (April 2008). "The antibacterial activity against MRSA strains and other bacteria of a <500 Da fraction from maggot excretions/secretions of Lucilia sericata (Diptera: Calliphoridae)". Microbes Infect. 10 (4): 325–33. doi:10.1016/j.micinf.2007.12.011. PMID 18400544.

[patent-3] "(WO2011042684) Antimicrobial Composition and a Method of Controlling Contamination and Infection Using Said Composition". US Patent. October 1, 2010. Retrieved 8 December 2012.

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