Phenylethylmalonamide
Appearance
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Names | |
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IUPAC name
2-Ethyl-2-phenylmalonamide
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Identifiers | |
3D model (JSmol)
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ChemSpider | |
ECHA InfoCard | 100.027.804 |
PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C11H14N2O2 | |
Molar mass | 206.24 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Phenylethylmalonamide (PEMA) is an active metabolite of the anticonvulsant drug primidone, although it is produced in a much lower concentration than phenobarbital, the other active metabolite.[1]
References
- ^ El-Masri HA, Portier CJ (June 1998). "Physiologically based pharmacokinetics model of primidone and its metabolites phenobarbital and phenylethylmalonamide in humans, rats, and mice". Drug Metab. Dispos. 26 (6): 585–94. PMID 9616196.