Antrodia cinnamomea

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Antrodia cinnamomea
Scientific classification
A. cinnamomea
Binomial name
Antrodia cinnamomea
Chang & Chou (1995)

Antrodia cinnamomea is a fungus species, also known as AC fungus, or AC mushroom .[1] It causes brown heart rot of aromatic tree Cinnamomum kanehirai. It is used in Taiwan medicine as a remedy for cancer, hypertension, and hangover.[2] Annual market is worth over $100 million (US) in Taiwan alone. Recently, the 32.15 Mb genome containing 9,254 genes was sequenced.[3]

Other than being a well-known remedy for cancer, hypertension, and hangover, AC fungus has been found to produces anti-obesogenic, anti-inflammatory and antidiabetic effects in HFD-fed mice.[4]


  1. ^ Chang, T.T.; Chou, W.N. (1995). "Antrodia cinnamomea sp. nov. on Cinnamomum kanehirai in Taiwan". Mycological Research. 99 (6): 756–758. doi:10.1016/S0953-7562(09)80541-8. ISSN 0953-7562.
  2. ^ Liu, Y. W.; et al. (2012). "Protective effects of Antrodia cinnamomea against liver injury". Journal of Traditional and Complementary Medicine. 2 (4): 284. doi:10.1016/s2225-4110(16)30114-6. PMC 3942906.
  3. ^ Lu, MY.; Fan, WL.; Wang, WF.; Chen, T.; Tang, YC.; Chu, FH.; Chang, TT.; Wang, SY.; Li, MY.; Chen, Y. H.; Lin, Z. S.; Yang, K. J.; Chen, S. M.; Teng, Y. C.; Lin, Y. L.; Shaw, J. F.; Wang, T. F.; Li, W. H. (Oct 2014). "Genomic and transcriptomic analyses of the medicinal fungus Antrodia cinnamomea for its metabolite biosynthesis and sexual development". Proc Natl Acad Sci U S A. 111 (44): E4743–52. doi:10.1073/pnas.1417570111. PMC 4226107. PMID 25336756.
  4. ^ C-J Chang, C-C Lu, C-S Lin, J Martel, Y-F Ko, DM Ojcius, T-R Wu, Y-H Tsai, T-S Yeh, J-J Lu, H-C Lai, and JD Young (2018). "Antrodia cinnamomea reduces obesity and modulates the gutmicrobiota in high-fat diet-fed mice" (PDF). International Journal of Obesity. 2018: 231–243.CS1 maint: multiple names: authors list (link)

Further reading[edit]

  • Chang, Tun-Tschu, and Wang, Wu-Rong. "Basidiomatal formation of Antrodia cinnamomea on artificial agar media." Botanical Bulletin of Academia Sinica 46 (2005).
  • Yang, Fan-Chiang; Huang, Hui-Chin; Yang, Ming-Je (2003). "The influence of environmental conditions on the mycelial growth of Antrodia cinnamomea in submerged cultures". Enzyme and Microbial Technology. 33 (4): 395–402. doi:10.1016/S0141-0229(03)00136-4. ISSN 0141-0229.
  • Lin, Ting-Yu; Chen, Chieh-Yin; Chien, Shih-Chang; Hsiao, Wen-Wei; Chu, Fang-Hua; Li, Wen-Hsiung; Lin, Chin-Chung; Shaw, Jei-Fu; Wang, Sheng-Yang (2011). "Metabolite Profiles for Antrodia cinnamomea Fruiting Bodies Harvested at Different Culture Ages and from Different Wood Substrates". Journal of Agricultural and Food Chemistry. 59 (14): 7626–7635. doi:10.1021/jf201632w. ISSN 0021-8561. PMID 21668009.
  • Chang, Tun-Tschu, and Wen-Neng Chou. "Antrodia cinnamomea reconsidered and A. salmonea sp. nov. on Cunninghamia konishii in Taiwan." Botanical Bulletin of Academia Sinica 45 (2004).