Blocking antibody
A blocking antibody is an antibody that does not have a reaction when combined with an antigen, but prevents other antibodies from combining with that antigen.[1]
The term can also be used for inhibiting antibody, prozone phenomenon and, agglutination reaction.
Blocking antibodies have been described as a mechanism for HSV-1 to evade the immune system.[2]
See also
References
- ^ Blocking+Antibodies at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
- ^ Hook LM, Huang J, Jiang M, Hodinka R, Friedman HM (July 2008). "Blocking antibody access to neutralizing domains on glycoproteins involved in entry as a novel mechanism of immune evasion by herpes simplex virus type 1 glycoproteins C and E". J. Virol. 82 (14): 6935–41. doi:10.1128/JVI.02599-07. PMC 2446985. PMID 18480440.
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