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Chemical probe

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Not to be confused with Hybridization probe.

Chemical probes are reagents that allow the user to probe into mechanistic and phenotypic questions about their molecular targets. They can rapidly and reversibly inhibit a protein or protein domain in cells.[1] They typically have an extremely high in vitro potency and have very high specificity relative to other proteins of the same family.[2]

References

  1. ^ "The promise and peril of chemical probes : Nature Chemical Biology : Nature Publishing Group". Nature.com. Retrieved July 27, 2015.
  2. ^ "Chemical Probes Versus Drugs. In the Pipeline:". Pipeline.corante.com. Retrieved July 27, 2015.
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