Chemical probe
Chemical probes are reagents that allow the user to probe into mechanistic and phenotypic questions about their molecular targets. They can rapidly and reversibly inhibit a protein or protein domain in cells.[1] They typically have an extremely high in vitro potency and have very high specificity relative to other proteins of the same family.[2] For more information about chemical probes in general or for specific advice about which chemical probes are most suited to an experiment, visit The Chemical Probes Portal.
References
- ^ "The promise and peril of chemical probes : Nature Chemical Biology : Nature Publishing Group". Nature.com. Retrieved July 27, 2015.
- ^ "Chemical Probes Versus Drugs. In the Pipeline:". Pipeline.corante.com. Retrieved July 27, 2015.