Dihydrolipoic acid

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Dihydrolipoic acid
Preferred IUPAC name
6,8-Bis(sulfanyl)octanoic acid
Other names
6,8-Dimercaptooctanoic acid (no longer recommended[1])
Reduced lipoic acid
462-20-4 YesY
ChEBI CHEBI:18047 YesY
ChEMBL ChEMBL225952 YesY
ChemSpider 408 YesY
ECHA InfoCard 100.120.390
Jmol 3D model Interactive image
KEGG C02147 YesY
MeSH Dihydrolipoic+acid
PubChem 421
Molar mass 208.343
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Dihydrolipoic acid is an organic compound that is the reduced form of lipoic acid. This carboxylic acid features a pair of thiol groups. It is optically active but only the R-enantiomer is biochemically significant. The lipoic acid/dihydrolipoic acid pair participate in a variety of biochemical transformations.

See also[edit]


  1. ^ Nomenclature of Organic Chemistry : IUPAC Recommendations and Preferred Names 2013 (Blue Book). Cambridge: The Royal Society of Chemistry. 2014. p. 697. doi:10.1039/9781849733069-FP001. ISBN 978-0-85404-182-4. The prefixes ‘mercapto’ (–SH), and ‘hydroseleno’ or selenyl (–SeH), etc. are no longer recommended.