The station is built as an underground viaduct supported on 220 piers
The station was opened as part of a branch of line 7 from Louis Blanc to Pré Saint-Gervais on 18 January 1911. The station is built in weak ground as it was formerly a mine, where gypsum was extracted from three layers for export to the United States. It is built with arches over each of the tracks to strengthen the station box, which are supported by 220 piers, 2.5 metres in diameter, with a cumulative height of 5,500 metres. On 3 December 1967 this branch was separated from line 7, becoming line 7bis.
It is named after the Place du Danube, named after the Danube River. This street was renamed the Place de Rhin-et-Danube in 1952, adding a reference to the Rhine.