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Debacterol and Oralmedic swabs and packaging.jpg
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Phenolsulfonic acid Sulfonic acid
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CAS Number 7664-93-9 YesY 1333-39-7
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Debacterol Canker Sore Pain Relief solution is a liquid topical agent that is used in the treatment of ulcerating oral mucosal lesions and minor oral abrasions.[1]


Debacterol is effective[2] in the treatment of recurrent aphthous stomatitis (Canker Sores). Debacterol usually comes in a swab form, but is also available in a vial. Its formulation is documented more deeply in U.S. Patent 6,596,299 and U.S. Patent 6,830,757.


One clinical trial comparing Debacterol to Kenalog-in-Orabase and a no-intervention control group found that patients treated with Debacterol reported significantly better relief of symptoms compared to the other two groups 3 days after treatment.[3] In the same study, 60% of ulcers treated with Debacterol had disappeared by day 6 compared to about 30% in the other groups.[3]

Debacterol appears to be more effective on mouth sores in areas of the mouth which have less saliva production. Since a mouth sore must be dry prior to application of Debacterol, the area under the tongue is difficult to get a solid application on. The length of time of pain relief and the overall effectiveness may be reduced in areas such as this.


  1. ^ "Debacterol product description". 
  2. ^ "The Miracle Canker Sore Remedy That Most Physicians Have Never Heard Of". October 2013. 
  3. ^ a b Rhodus, NL; Bereuter, J (December 1998). "An evaluation of a chemical cautery agent and an anti-inflammatory ointment for the treatment of recurrent aphthous stomatitis: a pilot study.". Quintessence international (Berlin, Germany : 1985). 29 (12): 769–73. PMID 10196853. 

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