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Virus classification
Group: Group II (ssDNA)
Order: Unassigned
Family: Parvoviridae
Subfamily: Densovirinae
Genus: Ambidensovirus
Type species
Lepidopteran ambidensovirus 1

The virus genus Ambidensovirus belongs to the Densovirinae subfamily which belongs to the Parvoviridae family. The viruses of this genus are single-stranded DNA viruses. This genus infects invertebrates, including crustaceans and insects. There are currently six species in this genus including the type species Lepidopteran ambidensovirus 1.[1][2]


Group: ssDNA



Virions consist of non-enveloped capsids that have a round appearance and display icosahedral symmetry.[3] The virions each have an isometric (and therefore spherical) nucleocapsid with a diameter of either 18–22 nm or 20–26 nm.[3] Sixty capsomers are present in each capsid.[3] The structure of each capsomer is described as "a quadrilateral 'kite-shaped' wedge"; the surface is said to have a rough appearance with small projections.[3] The centre of capsids are sometimes visualised as appearing dark due to stain penetration in preparations where only a single species is retrieved. The virions do not appear to contain lipids. The buoyant density (in CsCl) of the virions is 1.4–1.44 g cm−3.[3]

Genus Structure Symmetry Capsid Genomic Arrangement Genomic Segmentation
Ambidensovirus Icosahedral T=1 Non-Enveloped Linear Segmented


Ambidensoviruses are non-enveloped and have icosahedral capsids with T=1 symmetry. They have non-segmented genomes that contain a single linear molecule of single-stranded DNA. The genome codes for structural proteins are about 5000 nucleotides in length and could either be negative-sense or positive-sense. Conserved nucleotide sequences of usually 120–300 or more nucleotides are present at the 3'-terminus and an inverted repeat of this could also be found at the 5'-terminus.[3]

Life Cycle[edit]

Viral replication is nuclear. Entry into the host cell is achieved by attachment to host receptors, which mediates clathrin-mediated endocytosis. Replication follows the rolling-hairpin model. DNA-templated transcription, with some alternative splicing mechanism is the method of transcription. Insects serve as the natural host.[1]

Genus Host Details Tissue Tropism Entry Details Release Details Replication Site Assembly Site Transmission
Ambidensovirus Insects Variable Clathrin-mediated endocytosis uncertain Nucleus Nucleus Unknown


  1. ^ a b "Viral Zone". ExPASy. Retrieved 12 June 2015. 
  2. ^ a b ICTV. "Virus Taxonomy: 2014 Release". Retrieved 12 June 2015. 
  3. ^ a b c d e f "Densovirinae". ICTVdB—The Universal Virus Database, version 4. Retrieved 2007-05-15. 

External links[edit]