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Desymmetrization

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Desymmetrization in stereochemistry is the modification of a molecule which results in the loss of one or more symmetry elements, such as those which give rise to chirality (a mirror plane, center of inversion, rotation-reflection axis), as in the conversion of a prochiral molecular entity into a chiral one [1].

References

  1. ^ Basic Terminology of Stereochemistry, G.P. Moss Ed. Pure 19 Appl. Chem., Vol. 68, No. 12, pp. 2193-2222, 1996