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Etanidazole

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Etanidazole
Names
IUPAC name
N-(2-Hydroxyethyl)-2-(2-nitro-1H-imidazol-1-yl)acetamide
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.164.363 Edit this at Wikidata
UNII
  • InChI=1S/C7H10N4O4/c12-4-2-8-6(13)5-10-3-1-9-7(10)11(14)15/h1,3,12H,2,4-5H2,(H,8,13) checkY
    Key: WCDWBPCFGJXFJZ-UHFFFAOYSA-N checkY
  • O=[N+]([O-])c1nccn1CC(=O)NCCO
Properties
C7H10N4O4
Molar mass 214.181 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

Etanidazole is a nitroimidazole drug used for its radiosensitizing properties. Administration of etanidazole results in a decrease of glutathione concentration and inhibits glutathione S-transferase.[1] The result is that tissues become more sensitive to the ionizing radiation used in cancer treatment.

See also

References