FGF-1 internal ribosome entry site (IRES)
| FGF-1 internal ribosome entry site (IRES) | |
|---|---|
 Predicted secondary structure and sequence conservation of IRES_FGF1 | |
| Identifiers | |
| Symbol | IRES_FGF1 |
| Rfam | RF00387 |
| Other data | |
| RNA type | Cis-reg; IRES |
| Domain(s) | Eukaryota |
| GO | GO:0043022 |
| SO | SO:0000243 |
| PDB structures | PDBe |
The FGF-1 internal ribosome entry site (IRES) is an RNA element present in the 5' UTR of the mRNA of fibroblast growth factor-1 and allows cap-independent translation. It is thought that FGF-1 internal ribosome entry site (IRES) activity is strictly controlled and highly tissue specific.[1]
References
- ^ Martineau, Y; Le Bec C; Monbrun L; Allo V; Chiu IM; Danos O; Moine H; Prats H; Prats AC (2004). "Internal Ribosome Entry Site Structural Motifs Conserved among Mammalian Fibroblast Growth Factor 1 Alternatively Spliced mRNAs". Mol Cell Biol. 24 (17): 7622–7635. doi:10.1128/MCB.24.17.7622-7635.2004. PMC 507008. PMID 15314170.
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External links
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