English: This chart shows a hypothetical data set of 10 people and their cancer status. Here we are examining a suspect gene and 3 other genes that are suspected to be involved in the processes. Looking at the graph there is a clear connection between the suspect gene and Gene A, but there is also a less obvious interaction between the suspect gene and gene C that only takes place when gene B is absent. It is entirely possible that co-segregation would have a hard time determining that relationship. In a Real data set with hundreds or even thousands of genes being examined you could erroneously conclude that B contributes to the cancer when, in reality it does not.
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