English: Protein structure of human FAM86B1 isoform 1 predicted by AlphaFold. Colored by secondary structure, with alpha helices in red and beta strands in yellow. The SKL2 peroxisomal targeting signal is shown in green. Remaining coils are blue. gif shows FAM86B1 slowly spinning, so that the full 3D model can be seen.
AlphaFold papers:
Jumper, J et al. Highly accurate protein structure prediction with AlphaFold. Nature (2021).
Varadi, M et al. AlphaFold Protein Structure Database: massively expanding the structural coverage of protein-sequence space with high-accuracy models. Nucleic Acids Research (2021).
Model visualized using NCBI iCn3D protein visualizer. Papers:
Wang J, Youkharibache P, Zhang D, Lanczycki CJ, Geer RC, Madej T, Phan L, Ward M, Lu S, Marchler GH, Wang Y, Bryant SH, Geer LY, Marchler-Bauer A. iCn3D, a Web-based 3D Viewer for Sharing Representations of Biomolecular Structures. Bioinformatics. 2020 Jan 1; 36(1):131-135. (Epub 2019 June 20.) doi: 10.1093/bioinformatics/btz502. [PubMed PMID: 31218344]
Wang J, Youkharibache P, Marchler-Bauer A, Lanczycki C, Zhang D, Lu S, Madej T, Marchler GH, Cheng T, Chong LC, Zhao S, Yang K, Lin J, Cheng Z, Dunn R, Malkaram SA, Tai C-H, Enoma D, Busby B, Johnson NL, Tabaro F, Song G, Ge Y. iCn3D: From Web-Based 3D Viewer to Structural Analysis Tool in Batch Mode. Front. Mol. Biosci. 2022 9:831740. (Epub 2022 Feb 17.) doi: 10.3389/fmolb.2022.831740. [PubMed PMID: 35252351]
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