File:FragileX.png
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Summary
| Description |
English: Silencing of the FMR1 Gene in Fragile X Mental Retardation Syndrome: Artistic representation of events occurring during gene silencing in Fragile X mental retardation syndrome (FXS). The FMR1 gene, which is on the X chromosome, colocalizes with a fragile site seen in FXS cells that gives this disorder its name. FXS alleles become associated with SIRT1. SIRT1, a class III histone deacetylase, deacetylates lysine 9 of histone H3 and lysine 16 of histone H4, ultimately leading to chromatin compaction and gene silencing (see Biacsi et al., e1000017). doi:10.1371/image.pgen.v04.i03.g001 |
| Date | (UTC) |
| Source | http://www.plosgenetics.org/article/info:doi%2F10.1371%2Fimage.pgen.v04.i03 |
| Author | Dr. Marian L. Miller (Journal-Cover-Art.com). |
| Permission (Reusing this file) |
Per PLOS site: "All site content, except where otherwise noted, is licensed under a Creative Commons Attribution License." |
| Other versions | http://www.plosgenetics.org/article/slideshow.action?uri=info:doi/10.1371/image.pgen.v04.i03&imageURI=info:doi/10.1371/image.pgen.v04.i03.g001 |
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Original upload log
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| Date/Time | Dimensions | User | Comment |
|---|---|---|---|
| 2010-01-20 16:14 | 600×600× (300909 bytes) | ClockworkSoul | {{Information |Description = Silencing of the FMR1 Gene in Fragile X Mental Retardation Syndrome: Artistic representation of events occurring during gene silencing in Fragile X mental retardation syndrome (FXS). The FMR1 gene, which is on the X chromo |
File history
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 19:07, 5 August 2014 | | 600 × 600 (294 KB) | Mithril | Transferred from en.wikipedia |
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