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Figure 5. FLAIR (3T) and GRE phase (7T) images of a patient with active relapsing-remitting MS.

FLAIR images show numerous white matter MS lesions of which 2 are magnified (inset, red arrows). Phase imaging at 7T phase/GRE reveals a hypointense ring corresponding with one lesion on FLAIR. The other lesion is not visible on 7T GRE (inset, arrows).

Other info copied from article by uploader of file: Gradient-echo (GRE) phase imaging at ultra-highfield MRI is highly sensitive for iron. A number of GRE studies with MS patients and autoptic MS tissue, including our own have demonstrated that iron accumulates in white matter and cortical lesions.
Date Date of publication: 2013-05-14
Source Mehta V, Pei W, Yang G, Li S, Swamy E, et al. (2013) Iron Is a Sensitive Biomarker for Inflammation in Multiple Sclerosis Lesions. PLoS ONE 8(3): e57573. doi:10.1371/journal.pone.0057573. http://www.plosone.org/article/info:doi/10.1371/journal.pone.0057573#pone-0057573-g005
Author Veela Mehta, Wei Pei, Grant Yang, Suyang Li, Eashwar Swamy, Aaron Boster, Petra Schmalbrock, David Pitt
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Other versions Derivative works of this file:  Journal.pone.0057573.g005 cropped.png

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w:en:Creative Commons
attribution
This file is licensed under the Creative Commons Attribution 2.5 Generic license.
You are free:
  • to share – to copy, distribute and transmit the work
  • to remix – to adapt the work
Under the following conditions:
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current20:36, 18 May 2013Thumbnail for version as of 20:36, 18 May 2013909 × 588 (550 KB)Garrondo{{Information |Description ={{en|1=Description copied from the article: Figure 5. FLAIR (3T) and GRE phase (7T) images of a patient with active relapsing-remitting MS. FLAIR images show numerous white matter MS lesions of which 2 are magnified (i...

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