Fustin
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| Names | |
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| IUPAC name
2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-2,3-dihydrochromen-4-one
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| Other names
Dihydrofisetin
Tetrahydroxyflavanone 3,7,3',4'-Tetrahydroxyflavanone 2,3-Dihydrofisetin 3′,4′,7-trihydroxyflavanol | |
| Identifiers | |
3D model (JSmol)
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| ECHA InfoCard | 100.039.975 |
PubChem CID
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CompTox Dashboard (EPA)
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| Properties | |
| C15H12O6 | |
| Molar mass | 288.25 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Fustin, sometimes called "dihydrofisetin", is a flavan-on-ol, a type of flavonoid. It can be found in young fustic (Cotinus coggygria)[1] and in the lacquer tree[2] (Toxicodendron vernicifluum, aka Rhus verniciflua).
Fustin shows protective effects on 6-hydroxydopamine-induced neuronal cell death.[2]
Unlike Fisetin, fustin has no double bond in the C-ring. This makes fustin a flavan, with two stereocenters and four stereoisomers.
References
- ^ Phytochemical analysis of young fustic (Cotinus coggygria heartwood) and identification of isolated colourants in historical textiles, Lemonia Valianou, Konstantina Stathopoulou, Ioannis Karapanagiotis, Prokopios Magiatis, Eleni Pavlidou, Alexios-Leandros Skaltsounis and Yannis Chryssoulakis, 2009
- ^ a b Protective effects of fustin, a flavonoid from Rhus verniciflua Stokes, on 6-hydroxydopamine-induced neuronal cell death. Park BC, Lee YS, Park HJ, Kwak MK, Yoo BK, Kim JY, Kim JA. 2007