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Hughes–Stovin syndrome

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Hughes-Stovin syndrome is a rare disorder of unknown cause that is characterized by the combination of multiple pulmonary artery aneurysms and deep vein thrombosis. It is named after the two British physicians, John Patterson Hughes and Peter George Ingle Stovin, who first described it in 1959. It is a rare variant of Behçet's disease. Most patients are young adult males between the age of 20-40. Common clinical presentations include fever and haemoptysis. Radiological features are similar to those of Behçet's disease.[1]

Typical Symptoms

  • Multiple Pulmonary Aneurysms[2]
  • Peripheral Venous Thrombosis[2]
  • Recurrent Fever[2]
  • Chills[2]
  • Haemoptysis[2]
  • Cough[2]

In the Season 6 episode 11 "The Down Low" of the medical drama House, the patient is finally and accurately diagnosed with Hughes-Stovin Syndrome, but it is too far developed to be treated, and he dies within 24 hours.

References

  1. ^ http://www.medcyclopaedia.com/library/topics/volume_v_1/h/hughes_stovin_syndrome.aspx Medcyclopaedia Hughes-Stovin syndrome
  2. ^ a b c d e f National Centre for Biotechnology Information, http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2649053/