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Interferon-stimulated gene

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An interferon-stimulated gene (ISG) is a gene whose expression is stimulated by interferon.[1] The protein products of these genes control pathogenic infections.

ISG have been subdivided into type I (stimulated by IFN alpha, beta), type II (IFN gamma) and type III (IFN lambda).

See also

References

  1. ^ Schneider WM, Chevillotte MD, Rice CM (2014). "Interferon-stimulated genes: a complex web of host defenses". Annu. Rev. Immunol. 32: 513–45. doi:10.1146/annurev-immunol-032713-120231. PMC 4313732. PMID 24555472.


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