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John Pickard (neurosurgeon)

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John Pickard
Born
John Douglas Pickard

(1946-03-21) 21 March 1946 (age 78)
AwardsFellow of the Academy of Medical Sciences (1998)
Robert H Pudenz Award for Excellence in CSF Physiology (2000)
Guthrie Memorial Medal, Royal Army Medical Corps (2010)
Scientific career
InstitutionsUniversity of Cambridge
St Catharine's College

John Douglas Pickard CBE FRCS FMedSci (born 21 March 1946[1]) is a British professor emeritus of neurosurgery in the Department of Clinical Neurosciences of University of Cambridge.[2][3] He is the honorary director of the National Institute for Health Research (NIHR) Healthcare Technology Cooperative (HTC) for brain injury.[4] His research focuses on advancing the care of patients with acute brain injury, hydrocephalus and prolonged disorders of consciousness through functional brain imaging, studies of pathophysiology and new treatments; as well as focusing on health, economic and ethical aspects.[2]

Pickard is an emeritus professorial Fellow of St Catharine's College, Cambridge, having retired as a professorial fellow and director of studies in medical sciences.[5] He served as president of the Society of British Neurological Surgeons from 2006 to 2008.[6]

Education

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Pickard attended King George V Grammar School, Southport and then studied Natural Sciences at the University of Cambridge (Bachelor of Arts with First Class Honours in Physiology and Biophysics in 1967).[1] He then completed his Bachelor of Medicine and Surgery at King's College Hospital in London in 1970 and Master of Surgery (MChir with distinction for his thesis on ‘The Role of Prostaglandins in the Control of the Cerebral Circulation’) from the University of Cambridge in 1981.[7][8] He is a Fellow of the Royal College of Surgeons of Edinburgh since 1974 and England (Ad eundem) since 1989.[7] Since 1998, Pickard has been a Fellow of the Academy of Medical Sciences.[9]

Career

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Pickard trained in neurosurgery at the Institute of Neurological Sciences in Glasgow and at the University of Pennsylvania. He then became an honorary consultant neurosurgeon and senior lecturer, reader and professor of clinical neurology at the Wessex Neurological Centre and University of Southampton.[1] In 1991, he was appointed the first professor of neurosurgery at the University of Cambridge, based at Addenbrooke's Hospital.[10] His clinical practice included, at various times, subspecialty interests in neurovascular surgery, complex necks, hydrocephalus and tumours of the pituitary gland and IIIrd ventricle.[2]

With colleagues, Pickard established and was the first chairman and clinical director of the Wolfson Brain Imaging Centre (WBIC), a division of the University of Cambridge's Department of Clinical Neurosciences,[11] Pickard, in his capacity with the WBIC, worked with patients who were critically ill, the morbidly obese and patients with acute mental health and addiction problems.[12] From 2001 to 2013, Pickard was the National Health Service (NHS) divisional director for neurosciences at Addenbrooke's Hospital.[13] In 2009, Pickard became an NIHR senior investigator.[14] At the end of 2013, Pickard retired from full-time NHS practice and head of academic neurosurgery, but remained active in research as a voluntary director of research in the University of Cambridge.[15]

In 2013, Pickard became the first Cambridge HTC honorary director, which is one of eight national co-operatives that receive funding from the NIHR. The Cambridge HTC is the only HTC to focus on brain injury.[4][16]

In addition to his presidency of Society of British Neurological Surgeons (SBNS), Pickard was previously chairman of the Joint Neurosciences Council and remains the honorary civilian consultant for neurosurgery to the British Army.[17] Pickard was a member of the UK Government's Animal Procedures Committee and chaired a report into the assessment of cumulative severity and lifetime experience in non-human primates used in neuroscience. This report, also called the Pickard Report, was published in 2013.[18] In addition, Pickard was also president of Academia Eurasiana Neurochirurgica from 2011 to 2012.[19]

Pickard is a patron and former president of Cambridgeshire Headway,[20][21] a founder-trustee and chairman of the research committee of the Brain and Spine Foundation,[22] a trustee of the Brain Research Trust and was the first patron of Idiopathic Intracranial Hypertension (IIH) UK.[23]

Research

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Pickard's research focuses on the care of critically ill patients after brain injury.[17][24][25] He led the British Aneurysm Nimodipine trial (BRANT), which demonstrated that nimodipine reduces the incidence of poor outcomes after subarachnoid haemorrhage by 40 per cent.[26] His work has included definition of how early insults to the brain in both childhood and later life may lead to late changes in cognitive outcome and new ways of detecting when the blood supply to critical areas of the brain becomes a risk.[27] Pickard established and chairs the Impaired Consciousness Research Group in Cambridge,[28] which demonstrated that functional neuroimaging could be used to detect awareness in patients who are incapable of generating any recognisable behavioural response and appeared to be in a vegetative state.[29][30]

Pickard has also studied which parts of the brain are affected in normal pressure hydrocephalus[31] and novel treatments for pseudotumor cerebri and cerebral venous disorders.[3]

With others, Pickard established the Cambridge Shunt Evaluation Laboratory, which provides an international service for shunt testing in-vivo, and the UK Shunt Registry in 1994.[32][33] The formation of the Registry was funded by the UK Department of Health Medical Devices Agency and contains data on over 70,000 cerebrospinal fluid (CSF) shunt-related procedures.[33][34]

Pickard has published some 500[35] publications in scientific and medical journals, including Nature New Biology,[36] the British Medical Journal,[26] Nature,[37] Science,[29] Brain,[31] The Lancet[38] and the New England Journal of Medicine.[39] He has co-authored 6 books, including a monograph on 'Pseudotumor cerebri syndrome'.[6] He was formerly editor-in-chief of the series Advances in Technical Standards in Neurosurgery,[40] editor-in-chief of the British Journal of Neurosurgery (2000-2006) and neurosurgical editor of the Journal of Neurology, Neurosurgery, and Psychiatry.[10] The ISI Web of Science credits him with an h-index of 67.[41]

Honours and awards

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In 2000, Pickard received the Robert H. Pudenz Award for excellence in CSF physiology.[42] In 2008, he was awarded the Docteur Honoris Causa from the University of Liège, Belgium.[7] In 2010, Pickard was awarded the Guthrie Memorial Medal of the Royal Army Medical Corps[1] and named as one of Britain's top doctors by The Times.[43][44] In 2014, he received the Lifetime Achievement Appreciation Award from the International Society for Hydrocephalus and CSF Disorders.[7]

Pickard was appointed Commander of the Order of the British Empire (CBE) in the 2020 New Year Honours for services to neurosciences, neurosurgery and research for patients with complex neurological disorders.[45]

References

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  1. ^ a b c d "PICKARD, Prof. John Douglas". Oxford University Press. A & C Black. 2014. Retrieved 14 February 2015.
  2. ^ a b c "Profile: Professor John Pickard". Cambridge Neuroscience. Retrieved 10 January 2015.
  3. ^ a b "Profile: John Pickard". John van Geest Centre for Brain Repair. Retrieved 10 January 2015.
  4. ^ a b "Brain Injury Healthcare Technology Co-operative". National Institute for Health Research. Archived from the original on 14 February 2015. Retrieved 10 January 2015.
  5. ^ "Profile: Professor John Pickard". St Catharine's College Cambridge. Retrieved 10 January 2015.
  6. ^ a b "SBNS :: History". Society of British Neurological Surgeons. Retrieved 11 March 2015.
  7. ^ a b c d "Docteurs Honoris Causa 2008 – M. John Douglas Pickard". Universite de Liège (in French). 27 January 2009. Retrieved 10 January 2015.
  8. ^ Gelling, L; Shiel, A; Elliott, L; Owen, A; Wilson, B; Menon, D; Pickard, J (January 2004). "Commentary on Oh H. and Seo W. (2003) Sensory stimulation programme to improve recovery in comatose patients. Journal of Clinical Nursing 12, 394–404". Journal of Clinical Nursing. 13 (1): 125–7. doi:10.1046/j.1365-2702.2003.00832.x. hdl:10379/9206. PMID 14687306. S2CID 38785588.
  9. ^ "Fellow: Professor John Pickard FMedSci". The Academy of Medical Sciences. Retrieved 10 January 2015.
  10. ^ a b "Profile: John Douglas Pickard, MD". The Society of Neurological Surgeons. Retrieved 10 January 2015.
  11. ^ "About the WBIC". Wolfson Brain Imaging Centre. Retrieved 10 January 2015.
  12. ^ "Signs of Life". University of Cambridge. 27 June 2003. Retrieved 13 January 2015.
  13. ^ "Board of Governors Medical Director's Annual Report 2008" (PDF). Cambridge University Hospitals. 4 December 2008. Retrieved 10 January 2015.
  14. ^ "NIHR Senior Investigators 2009" (PDF). National Institute for Health Research. Archived from the original (PDF) on 18 April 2015. Retrieved 10 January 2015.
  15. ^ "Professor Pickard Retires". SINAPSE. Retrieved 10 January 2015.
  16. ^ "Cambridge project offers fresh hope for patients with brain injuries". Cambridge News. 9 December 2013. Retrieved 10 January 2015.
  17. ^ a b "Archibald Clark-Kennedy Lecture by Professor John Pickard, 16th February, 2013". Cambridge Neuroscience. 5 February 2013. Retrieved 10 January 2015.
  18. ^ Ettinger, Joshua (10 February 2014). "U.K. Report on Use of Primates in Research Challenges Notion of Cumulative Suffering". AAAS. Retrieved 10 January 2015.
  19. ^ "Past-Presidents". Academia Eurasiana Neurochirurgica. Retrieved 10 January 2015.
  20. ^ "Headway Cambridgeshire's New Patron". Headway Cambridgeshire. 15 October 2011. Retrieved 10 January 2015.
  21. ^ "Mind Your Head campaign launches in Cambridgeshire to find solutions to the dangers of brain trauma". Cambridge News. 9 May 2014. Retrieved 10 January 2015.
  22. ^ Hamlyn, Peter J (2012). "The Brains of Britain: Facts about the brain and its spine" (PDF). Spine Surgery London. Brain and Spine Foundation. Retrieved 10 January 2015.
  23. ^ "Sarah Hibberd played rugby for Henley Hawks Women's Rugby Team". Idiopathic Intracranial Hypertension UK. Retrieved 10 January 2015.
  24. ^ Steiner, LA; Czosnyka, M; Piechnik, SK; Smielewski, P; Chatfield, D; Menon, DK; Pickard, JD (2002). "Continuous monitoring of cerebrovascular pressure reactivity allows determination of optimal cerebral perfusion pressure in patients with traumatic brain injury". Critical Care Medicine. 30 (4): 733–8. doi:10.1097/00003246-200204000-00002. PMID 11940737. S2CID 19175665.
  25. ^ Quested, Tony (29 January 2014). "Cambridge study to give every Schumacher personalised treatment". Business Weekly. Retrieved 10 January 2015.
  26. ^ a b Pickard, JD; Murray, GD; Illingworth, R; Shaw, MD; Teasdale, GM; Foy, PM; Humphrey, PR; Lang, DA; Nelson, R; Richards, P (1989). "Effect of oral nimodipine on cerebral infarction and outcome after subarachnoid haemorrhage: British aneurysm nimodipine trial". BMJ. 298 (6674): 636–42. doi:10.1136/bmj.298.6674.636. PMC 1835889. PMID 2496789.
  27. ^ Pickard, JD; Matheson, M; Patterson, J; Wyper, D (1980). "Prediction of late ischemic complications after cerebral aneurysm surgery by the intraoperative measurement of cerebral blood flow". Journal of Neurosurgery. 53 (3): 305–8. doi:10.3171/jns.1980.53.3.0305. PMID 7420145. S2CID 33506496.
  28. ^ "The Impaired Consciousness Research Group". Wolfson Brain Imaging Centre. Retrieved 10 January 2015.
  29. ^ a b Owen, AM; Coleman, MR; Boly, M; Davis, MH; Laureys, S; Pickard, JD (2006). "Detecting awareness in the vegetative state". Science. 313 (5792): 1402. CiteSeerX 10.1.1.1022.2193. doi:10.1126/science.1130197. PMID 16959998. S2CID 54524352.
  30. ^ "BBC Panorama highlights innovative brain function research at Addenbrooke's". Cambridge University Hospitals. 14 November 2012. Retrieved 10 January 2015.
  31. ^ a b Momjian, S; Owler, BK; Czosnyka, Z; Czosnyka, M; Pena, A; Pickard, JD (2004). "Pattern of white matter regional cerebral blood flow and autoregulation in normal pressure hydrocephalus". Brain. 127 (Pt 5): 965–72. doi:10.1093/brain/awh131. PMID 15033897.
  32. ^ Czosnyka, M; Czosnyka, Z; Whitehouse, H; Pickard, JD (1997). "Hydrodynamic properties of hydrocephalus shunts: United Kingdom Shunt Evaluation Laboratory". Journal of Neurology, Neurosurgery, and Psychiatry. 62 (1): 43–50. doi:10.1136/jnnp.62.1.43. PMC 486694. PMID 9010399.
  33. ^ a b Pickard, JD; Richards, HK (2001). "Principles of quality management in medicine: the British concept". Acta Neurochirurgica. Supplement. 78: 45–52. doi:10.1007/978-3-7091-6237-8_7. ISBN 978-3-7091-7275-9. PMID 11840730.
  34. ^ Richards, H; Seeley, H; Pickard, J (2010). "Are adjustable valves effective in all ages of patient? Data from the UK Shunt Registry". Cerebrospinal Fluid Research. 7 (Suppl 1): S40. doi:10.1186/1743-8454-7-S1-S40. PMC 3026519.
  35. ^ "John D Pickard – List of Publications". Microsoft Academic Search.
  36. ^ Pickard, JD; Mackenzie, ET (1973). "Inhibition of prostaglandin synthesis and the response of baboon cerebral circulation to carbon dioxide". Nature New Biology. 245 (145): 187–8. doi:10.1038/newbio245187a0. PMID 4200498.
  37. ^ Pickard, JD; Gillard, JH (2005). "Guidelines reduce the risk of brain-scan shock". Nature. 435 (7038): 17. Bibcode:2005Natur.435...17P. doi:10.1038/435017a. PMID 15874992.
  38. ^ Higgins, JN; Owler, BK; Cousins, C; Pickard, JD (2002). "Venous sinus stenting for refractory benign intracranial hypertension". The Lancet. 359 (9302): 228–30. doi:10.1016/s0140-6736(02)07440-8. PMID 11812561. S2CID 12998222.
  39. ^ Monti, MM; Vanhaudenhuyse, A; Coleman, MR; Boly, M; Pickard, JD; Tshibanda, L; Owen, AM; Laureys, S (2010). "Willful modulation of brain activity in disorders of consciousness". N Engl J Med. 362 (7): 579–89. doi:10.1056/nejmoa0905370. PMID 20130250. S2CID 13358991.
  40. ^ Pickard, JD; Akalan, N; Benes, V; Di Rocco, C; Dolenc, VV; Antunes, JL; Johannes, J; Sindou, M (2010). Advances and Technical Standards in Neurosurgery: Volume 36. Austria: Springer Science & Business Media. ISBN 978-3709101797.
  41. ^ "John D Pickard – Citation Report". Web of Science. Retrieved 11 January 2015.
  42. ^ "Hydrocephalus News Letter". 2010. Retrieved 11 January 2015.
  43. ^ Grainger, Lisa (13 November 2010). "Britain's top doctors directory". The Times. Retrieved 11 January 2015.
  44. ^ "The Times: Six CUH doctors are best in Britain". Cambridge University Hospitals. 16 November 2010. Archived from the original on 28 November 2010. Retrieved 11 January 2015.
  45. ^ "No. 62866". The London Gazette (Supplement). 28 December 2019. p. N10.
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