Littoral cell angioma
| Littoral cell angioma |
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Littoral cell angioma, abbreviated LCA, and formally known as littoral cell angioma of the spleen, is a benign tumour of the spleen that arises from the cells that line the red pulp.[1]
Symptoms
LCAs can manifest with splenomegaly, persistent fever and weight loss.[2]
Some patients show no symptoms and the tumours are found incidentally.
Diagnosis
Littoral cell angiomas show in CT scans. They are diagnosed by pathologists by taking a sample of the tumour via Fine Needle Aspiration or Core Needle Aspiration. Histologically, they have anastoming small vascular channels and cystic spaces with papillary projections.[2]
Treatment
The treatment for a littoral cell angioma is a splenectomy.
If they do not cause the patient any problems, the spleen can remain and the tumours can be monitored for changes with regular CT scans.
See also
Additional images
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References
- ^ Tan, YM.; Chuah, KL.; Wong, WK. (Jul 2004). "Littoral cell angioma of the spleen" (PDF). Ann Acad Med Singap. 33 (4): 524–6. PMID 15329769.
- ^ a b Dascalescu, CM.; Wendum, D.; Gorin, NC. (Sep 2001). "Littoral-cell angioma as a cause of splenomegaly". N Engl J Med. 345 (10): 772–3. doi:10.1056/NEJM200109063451016. PMID 11547761.