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Multinodular goitre

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A multinodular goiter is a multinodular enlargement of the thyroid gland.[1]

The multinodular goiter can be associated with hyperthyroidism ("Toxic multinodular goitre") or not.

It is a non-tumoral condition but a thyroid cancer is identified in 13.7% of the patients operated for multinodular goiter. these nodules grow up at varying rates and secrete thyroid hormone autonomously thereby suppressing TSH dependent growth and function in the rest of gland. [2]

References

  1. ^ Frilling, A; Liu, C; Weber, F (2004). "Benign multinodular goiter". Scandinavian journal of surgery : SJS : official organ for the Finnish Surgical Society and the Scandinavian Surgical Society. 93 (4): 278–81. PMID 15658668.
  2. ^ Gandolfi, P. P.; Frisina, A; Raffa, M; Renda, F; Rocchetti, O; Ruggeri, C; Tombolini, A (2004). "The incidence of thyroid carcinoma in multinodular goiter: Retrospective analysis". Acta bio-medica : Atenei Parmensis. 75 (2): 114–7. PMID 15481700.

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