Mutacin 1140
| Names | |
|---|---|
| Systematic IUPAC name
L-Phenylalanyl-L-lysyl-D-cysteinyl-L-tryptophyl-2,3-didehydroalanyl-L-leucyl-L-cysteinyl-(2S)-2-amino-3-mercaptobutanoyl-L-prolylglycyl-L-cysteinyl-L-alanyl-L-arginyl-(2Z)-2-amino-2-butenoylglycyl-D-cysteinyl-L-phenylalanyl-L-asparaginyl-D-cysteinyl-L-tyrosyl-N-[(1Z)-2-mercaptoethenyl]-L-cysteinamide, cyclic (37),(811),(16213),(19211)-tetrakis(thioether) | |
| Other names
MU1140
| |
| Identifiers | |
| Properties | |
| C103H138N28O23S4 | |
| Molar mass | 2264.65 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
| |
Mutacin 1140 is a bacteriocin produced by Streptococcus mutans.[1] It has activity against a broad spectrum of Gram-positive bacteria. It is a member of the class of compounds known as lantibiotics.
References
- ^ Smith, L; Zachariah, C; Thirumoorthy, R; Rocca, J; Novák, J; Hillman, JD; Edison, AS (2003). "Structure and dynamics of the lantibiotic mutacin 1140". Biochemistry. 42 (35): 10372–84. doi:10.1021/bi034490u. PMID 12950164.
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