NIM811
Appearance
Identifiers | |
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3D model (JSmol)
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ChEMBL | |
PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C62H111N11O12 | |
Molar mass | 1202.61 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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NIM811 is a mitochondrial permeability transition inhibitor. Also known as N-methyl-4-isoleucine cyclosporin, it is a four-substituted cyclosporine analogue that binds to cyclophilin, however this binary complex cannot bind to calcineurin, and therefore lacks immunosuppressive activity.