Jump to content

Niementowski quinazoline synthesis

From Wikipedia, the free encyclopedia

This is an old revision of this page, as edited by 2a01:1d8::30 (talk) at 08:35, 26 January 2016 (I added an alternative name for dihydroquinazolines.). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

Niementowski quinazoline synthesis
Named after Stefan Niementowski
Reaction type Ring forming reaction

The Niementowski quinazoline synthesis is the chemical reaction of anthranilic acids with amides to form 4-oxo-3,4-dihydroquinazolines (3H-quinazolin-4-ones).[1][2][3]

The Niementowski quinazoline synthesis
The Niementowski quinazoline synthesis

References

  1. ^ Niementowski, Stefan (1895). "Synthesen von Chinazolinverbindungen". J. Prakt. Chem. 51: 564.
  2. ^ Williamson, T. A. (1957). "The chemistry of quinazoline". Heterocyclic Compounds. 6: 331.
  3. ^ Cuny, Eckehard; Lichtenthaler, F.W.; Moser, Alfred (1980). "Benzologs of allopurinol: Synthesis of pyrazolo [4,3-g] and [3,4-f] quinazolinones". Tetrahedron Lett. 21 (32): 3029. doi:10.1016/S0040-4039(00)77398-9.

See also