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Ophiorrhiza

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Ophiorrhiza
Ophiorrhiza mungos
Scientific classification
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Genus:
Ophiorrhiza

Species

About 150,[1] see text

Ophiorrhiza is a genus of flowering plants in the coffee (Rubiaceae) family. Species of the genus contain camptothecin, an alkaloid used to make chemotherapeutic agents.[2][3] So many of Ophiorrhiza species are endemic to certain areas of western Ghats. Species include:

References

  1. ^ a b Beegum, A. S., et al. (2007). Organogenesis from leaf and internode explants of Ophiorrhiza prostrata, an anticancer drug (camptothecin) producing plant. Electronic Journal of Biotechnology 10:1.
  2. ^ a b Joseph, G. and J. P. Joseph. Rediscovery of Ophiorrhiza caudata (Rubiaceae) from the Western Ghats of Kerala. Rheedia 19 45.
  3. ^ Viraporn, V., et al. (2010). Correlation of camptothecin-producing ability and phylogenetic relationship in the genus Ophiorrhiza. Planta Med. in pub.
  4. ^ a b c Sirikantaramas, S., et al. (2008). Mutations in topoisomerase I as a self-resistance mechanism coevolved with the production of the anticancer alkaloid camptothecin in plants. PNAS 105:18 6782.
  5. ^ a b c Arbain, D, et al. (1998). Unusual indole alkaloids from Ophiorrhiza blumeana Korth. J. Chem. Soc., Perkin Trans 1.
  6. ^ Asano, T., et al. (2004). Camptothecin production by in vitro cultures of Ophiorrhiza liukiuensis and O. kuroiwai. Plant Biotechnology 21:4 275.
  7. ^ Chu, F., et al. (2006). Taxonomic Status of Ophiorrhiza michelloides (Masam.) X. R. Lo (Rubiaceae) in Taiwan. Taiwania 51:2 143.
  8. ^ Nakamura, K., et al. (2006). Phylogenetic systematics of the monotypic genus Hayataella (Rubiaceae) endemic to Taiwan. Journal of Plant Research 119:657–661.
  9. ^ Nakamura, K., et al. (2006). Homostyly and autogamy in Ophiorrhiza pumila (Rubiaceae) in the Ryukyu Archipelago. Journal of Japanese Botany 81:113–120.