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Organification

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Organification is a biochemical process that takes place in thyroid glands. It is the incorporation of iodine into thyroglobulin for the production of thyroid hormone, a step done after the oxidation of iodide by the enzyme thyroid peroxidase (TPO).[1] Since iodine is an inorganic compound, and is being attached to thyroglobulin, a protein, the process is termed as "organification of iodine".[2]

References

  1. ^ Comprehensive Pharmacy Review, Leon Shargel, 6th edition, p1181.
  2. ^ Endocrine Physiology, Patricia E. Molina, third edition, p81.
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