Orthoreovirus
Template:Taxobox begin
Template:Taxobox begin placement virus
Template:Taxobox group iii entry
Template:Taxobox familia entry
Template:Taxobox genus entry
Template:Taxobox end placement
Template:Taxobox section subdivision
Mammalian orthoreovirus
Avian orthoreovirus
Template:Taxobox end
Orthoreoviruses are members of the Reoviridae virus family. They have double stranded RNA genomes and are therefore group III viruses. These viruses infect vertebrates (including humans) but no disease symptoms are normally seen. In some cases however, orthoreovirus infection can lead to complications.
The structure of the virus particles is complex. The virus is non-enveloped and has icosahedral symmetry with a triangulation number of 13. It can be compared to a wheel with spokes radiating out of it. The virus has a double protein shell. The outer shell is approximately 80nm in diameter and the inner shell is 60nm in diameter.
The genome can be divided into three main classes: L (large), M (medium) and S (small). The L genes encode λ proteins, the M genes encode μ proteins and the S genes encode δ proteins. δ1, δ3, λ2 and μ1c proteins make up in the outer capsid. Proteins λ1, λ3, δ2 and μ2 make up in inner capsid.
Replication of the virus takes place in the host cell cytoplasm.
External links
 | This article has not been added to any content categories. Please help out by adding categories to it so that it can be listed with similar articles. |