Pathway Genomics

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Pathway OME Corporation
Industry Biotechnology
Founded 2009 (2009)
Founder Michael Nova
Headquarters San Diego, California, United States

Pathway OME is a privately held global precision medical diagnostic company with mobile applications designed to empower physicians and their patients to take control of their health and wellness. Based in San Diego, California, the company offers genetic testing and Artificial Intelligence to physicians for their patients to support treatment a variety of health conditions. The test menu ranges from somatic and hereditary cancer, including BRCA1 and BRCA2, to pharmacogenomics testing for well-known drugs like Plavix, codeine, lamotrigine, to general health and wellness testing which includes information on a number of health conditions including type 1 and type 2 diabetes and hypertension.

Pathway OME owns and operates a clinical laboratory"Pathway Lab" accredited by the College of American Pathologists (CAP) and Clinical Laboratory Improvement Amendments (CLIA)[1] which “provides physicians and their patients with actionable and accurate precision healthcare information to improve or maintain, health and wellness in more than 40 different countries.”[2]


The company was founded with the vision to make “genetic testing and personalized medicine accessible and affordable to everyone.”[3] Pathway Genomics’ testing services cover a variety of conditions including somatic & hereditary cancer risk, cardiac health, inherited diseases, nutrition and exercise response, as well as drug response.[4]

In addition to continual testing improvements and new testing developments, Pathway Genomics is also currently developing OME™. OME is the “world’s only mobile healthcare consumer application with artificial intelligence to help provide consumers with personalized health and wellness information.[5]

IBM Partnership[edit]

In 2014, IBM Watson Group announced its partnership with Pathway Genomics, to help “deliver the first-ever cognitive consumer-facing app based on genetics from a user’s personal makeup.”[6] The mobile app, subsequently named OME, is the first of its kind to merge artificial intelligence and deep learning, powered by IBM Watson, with personal genetic information. It provides users with personalized health and wellness information based on the individual’s health history.[7]


General Health & Wellness
Tests in this category analyze a variety of genomic markers selected to give patients and providers a better understanding of a patient’s risk for a number of health conditions. These tests help individuals to better understand their genetic propensity to specific diets, eating behaviors, nutritional needs, exercise activity and various health conditions, which is important for true, long-term, overall health and success in weight management.[8]

  • Cardiac DNA Insight™
  • Cardiac Healthy Weight DNA Insight™
  • Carrier Status DNA Insight™
  • Healthy Weight DNA Insight™
  • Healthy Woman DNA Insight™
  • Pathway Fit®
  • SkinFit™

Pharmacogenomic testing provides physicians with information about how their patient’s body responds to commonly prescribed pain, mental health, and cardiac-related medications.[9]

  • Cardiac DNA Insight™
  • Medication DNA Insight™
  • Mental Health DNA Insight™
  • Pain Medication DNA Insight™

Liquid Biopsy
The CancerIntercept™ tests are 96-mutation panels designed for the detection of somatic mutations in a set of 9 driver genes involved primarily in breast, ovarian, lung, and colorectal cancers, and melanoma. These tests, which must be ordered by a physician, may be used to either monitor patients already diagnosed with cancer or potentially detect undiagnosed cancer. Results are available within 2–3 weeks.[10]

  • CancerIntercept™ Detect
  • CancerIntercept™ Monitor

Hereditary Cancer Tests
Hereditary cancer testing is offered to patients with a personal and/or family history suggestive of cancer. These testing options include targeted panels, full gene panels, and a number of reflexive testing options.[11]

  • BreastTrue™ High Risk Panel
  • BRCATrue™
  • BRCATrue™ Ashkenazi Jewish (3-Site)
  • BRCATrue™ Hispanic (8-Site)
  • ColoTrue™
  • LynchSyndromeTrue™

Carrier Screening
Carrier DNA Insight® is a comprehensive preconception and prenatal carrier screening test. Carrier DNA Insight® follows the American College of Obstetricians and Gynecologists (ACOG) recommendations, and screen patients for more than 70 recessive genetic diseases. Carrier DNA Insight® provides physicians with information about the risks of inherited diseases of their patients’ future children.[12]

  • Carrier DNA Insight®


Pathway Genomics’ executives include Vadim Sulman (CEO), Mark Adamshek (Dir Finance), Glenn D. Braunstein, M.D. (Chief Medical Officer), Michael Nova, M.D. (Chief Innovation Officer and Founder), Anja Kammesheidt, Ph.D. (Chief Scientific Officer), Nilesh Dharajiya, M.D. (Chief Laboratory Officer & Medical Director), Mitch Mulanix (Vice President of Business Development and Government Relations) and Michael H. Cox, CIPP (Privacy SoCal Privacy Consultants). [13]

See also[edit]

Single-nucleotide polymorphism (SNP)
Genetic counseling
Genomic counseling


  1. ^ "[1]." Licenses/Accreditations. Retrieved August 1, 2015.
  2. ^ "[2]." Press releases. Retrieved September 1, 2015.
  3. ^ "[3]." James Plante, Founder and CEO. Retrieved July 12, 2015.
  4. ^ "[4]." Our tests. Retrieved July 7, 2015.
  5. ^ "[5]." OME™ Cognitive Mobile Health & Wellness. Retrieved August 8, 2015.
  6. ^ "[6]." IBM Watson Group Invests in Pathway Genomics to Help Personalize Consumer Health. Press Release; IBM. Nov 12 2014. Retrieved June 24, 2015.
  7. ^ "[7]." OME™ Cognitive Mobile Health & Wellness. Retrieved August 8, 2015.
  8. ^ "[8]." DNA Insight™ General Health & Wellness Genetics Tests. Retrieved March 5, 2015.
  9. ^ "[9]." DNA Insight™ Pharmacogenomics Tests. Retrieved June 1, 2015.
  10. ^ "[10]." Pathway Genomics – Liquid Biopsy CancerIntercept™. Retrieved September 10, 2015.
  11. ^ "[11]." True™ Hereditary Cancer Tests. Retrieved August 1, 2015.
  12. ^ "[12]." Carrier Screening. Retrieved May 16, 2016.
  13. ^ Management Team. Retrieved May 16, 2016.