Philip Kocienski
Philip Kocienski | |
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Born | 1946 |
Alma mater | |
Awards |
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Scientific career | |
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Thesis | Part I : The reactions of Di-t-butylcyclopropenyl cations with nucleophiles. Part II : The peracid oxidation of cyclopropenes[1] (1972) |
Doctoral advisor | Joseph Ciabattoni |
Philip Joseph Kocienski FRS (born 1946) is a British organic chemist. He is an Emeritus Professor at the University of Leeds.[3]
Research
Kocienski has made contributions to the design and development of new organometallic reagents in synthesis, and the applications of synthetic methods to complex natural products. Early work with Basil Lythgoe on the scope and stereochemistry of the Julia olefination with alpha-metallated sulphone reagents emphasised the value of this method in organic chemistry. His major contribution has been to research the synthesis and chemistry of novel metallated (lithium, copper and nickel) enol ethers, and to develop the uses of these intermediates in the synthesis of oxacyclic and geometrically defined alkene units in natural products of biological significance. Kocienski has synthesised the insecticide milbemycin beta 3, the potassium channel blocker talaromycin B, the hypotensive agent lacrimin, and the antihypertensive agent zoapatanol. His total synthesis of the insect toxin pederin, and his synthetic work toward the immunosuppressant FK 506, have made him regarded as one of the leading organic chemists in the field.[4]
Awards and honours
In 1984 Kocienski received the Hickinbottom Fellowship of the Royal Society of Chemistry.[5] He was elected a Fellow of the Royal Society (FRS) in 1997.[4]
References
- ^ Brown University Library, retrieved 2016-03-13.
- ^ Philip Kocienski, University of Glasgow, retrieved 2016-03-13.
- ^ Alphabetical staff list, University of Leeds, retrieved 2016-03-13.
- ^ a b "Philip Kocienski". London: Royal Society. One or more of the preceding sentences may incorporate text from the royalsociety.org website where "all text published under the heading 'Biography' on Fellow profile pages is available under Creative Commons Attribution 4.0 International License." "Royal Society Terms, conditions and policies". Archived from the original on February 20, 2016. Retrieved 2016-03-09.
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