The station was opened on July 13, 1913 as part of the original section of line 8 between Beaugrenelle (now Charles Michels) and Opéra. On July 29, 1937, line 10 was extended from Duroc to La Motte-Picquet - Grenelle; and the section of line 8 between La Motte-Picquet - Grenelle and Porte d'Auteuil, including Beaugrenelle was rerouted to the line 10.
The station was named Beaugrenelle, after Place Beaugrenelle, the former name of Place Charles Michels. "Beaugrenelle" (beautiful Grenelle) was a name given by property developers in the Grenelle district during its urbanisation. In 1945, it was renamed after Charles Michels (1903–1941), who had been elected Député for the 15th arrondissement of Paris by the Popular Front; He was taken hostage and shot by the Nazis.