Popeye protein conserved region

Popeye protein conserved region
Popeye protein conserved region
Identifiers
Symbol	Popeye

Popeye protein conserved region is a family of evolutionarily related proteins.

The Popeye (POP) family of proteins, is restricted to vertebrates and is preferentially expressed in developing and adult striated muscle. It is represented by a conserved region which includes three potential transmembrane domains.^[1] The strong conservation of POP genes during evolution and their preferential expression in heart and skeletal muscle suggest that these novel proteins may have an important function in these tissues in vertebrates.

Examples

Human genes encoding proteins containing this domain include:

BVES
POPDC2, POPDC3

References

^ Andree B, Hillemann T, Kessler-icekson G, Schmitt-john T, Jockusch H, Arnold HH, Brand T (2000). "Isolation and characterization of the novel popeye gene family expressed in skeletal muscle and heart". Dev. Biol. 223 (2): 371–382. doi:10.1006/dbio.2000.9751. PMID 10882522.

This article incorporates text from the public domain Pfam and InterPro: IPR006916

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[PUB00008654-1] Andree B, Hillemann T, Kessler-icekson G, Schmitt-john T, Jockusch H, Arnold HH, Brand T (2000). "Isolation and characterization of the novel popeye gene family expressed in skeletal muscle and heart". Dev. Biol. 223 (2): 371–382. doi:10.1006/dbio.2000.9751. PMID 10882522.

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