R1162-like plasmid antisense RNA
Appearance
R1162-like plasmid antisense RNA | |
---|---|
![]() Predicted secondary structure and sequence conservation of Plasmid_R1162 | |
Identifiers | |
Symbol | Plasmid_R1162 |
Rfam | RF00043 |
Other data | |
RNA type | Gene; antisense |
Domain(s) | Bacteria |
SO | SO:0001263 |
PDB structures | PDBe |
R1162-like plasmid antisense RNA is a 75-base RNA molecule which negatively regulates the RepI region of the plasmid.[1] The protein product of this gene region, along with another protein, controls the copy number of the 8.75kB R1162 plasmid.[2]
Experimental evidence has shown that in Escherichia coli, when levels of this RNA are decreased, the plasmid copy number of R1162 is increased.[1]
References
- ^ a b Kim, K; Meyer RJ (1986). "Copy-number of broad host-range plasmid R1162 is regulated by a small RNA". Nucleic Acids Res. 14 (20): 8027–8046. doi:10.1093/nar/14.20.8027. PMC 311832. PMID 2430262.
- ^ Kim, K; Meyer, RJ (Oct 20, 1985). "Copy number of the broad host-range plasmid R1162 is determined by the amounts of essential plasmid-encoded proteins". Journal of Molecular Biology. 185 (4): 755–67. doi:10.1016/0022-2836(85)90060-9. PMID 2932556.
External links