R1162-like plasmid antisense RNA
| R1162-like plasmid antisense RNA | |
|---|---|
 Predicted secondary structure and sequence conservation of Plasmid_R1162 | |
| Identifiers | |
| Symbol | Plasmid_R1162 |
| Rfam | RF00043 |
| Other data | |
| RNA type | Gene; antisense |
| Domain(s) | Bacteria |
| SO | SO:0001263 |
| PDB structures | PDBe |
R1162-like plasmid antisense RNA is a 75-base RNA molecule which negatively regulates the RepI region of the plasmid.[1] The protein product of this gene region, along with another protein, controls the copy number of the 8.75kB R1162 plasmid.[2]
Experimental evidence has shown that in Escherichia coli, when levels of this RNA are decreased, the plasmid copy number of R1162 is increased.[1]
References
- ^ a b Kim, K; Meyer RJ (1986). "Copy-number of broad host-range plasmid R1162 is regulated by a small RNA". Nucleic Acids Res. 14 (20): 8027–8046. doi:10.1093/nar/14.20.8027. PMC 311832. PMID 2430262.
- ^ Kim, K; Meyer, RJ (Oct 20, 1985). "Copy number of the broad host-range plasmid R1162 is determined by the amounts of essential plasmid-encoded proteins". Journal of Molecular Biology. 185 (4): 755–67. doi:10.1016/0022-2836(85)90060-9. PMID 2932556.
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