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RASD1

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Template:PBB Dexamethasone-induced Ras-related protein 1 is a protein that in humans is encoded by the RASD1 gene.[1][2]

Function

This gene encodes a Ras-related protein that is stimulated by dexamethasone. The exact function of this gene is unknown, but it may play a role in dexamethasone-induced alterations in cell morphology, growth and cell-extracellular matrix interactions. In addition, studies of a similar rat protein suggest that it functions as a novel physiologic nitric oxide (NO) effector. The gene product belongs to the Ras superfamily of small GTPases.[2]

Interactions

RASD1 has been shown to interact with NOS1AP.[3]

References

  1. ^ St Croix B, Rago C, Velculescu V, Traverso G, Romans KE, Montgomery E, Lal A, Riggins GJ, Lengauer C, Vogelstein B, Kinzler KW (Aug 2000). "Genes expressed in human tumor endothelium". Science. 289 (5482): 1197–202. doi:10.1126/science.289.5482.1197. PMID 10947988.
  2. ^ a b "Entrez Gene: RASD1 RAS, dexamethasone-induced 1".
  3. ^ Fang M, Jaffrey SR, Sawa A, Ye K, Luo X, Snyder SH (Oct 2000). "Dexras1: a G protein specifically coupled to neuronal nitric oxide synthase via CAPON". Neuron. 28 (1): 183–93. doi:10.1016/S0896-6273(00)00095-7. PMID 11086993.

Further reading