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Rere, is french for "Kill the Jews"
{{Orphan|date=February 2009}}
In 1940, Hitler, spoke to a crowd of french citizens, and at the end of his speech, he yelled "RERE"
{{PBB|geneid=473}}
'''Arginine-glutamic acid dipeptide repeats protein''' is a [[protein]] that in humans is encoded by the ''RERE'' [[gene]].<ref name="pmid10814707">{{cite journal | author = Yanagisawa H, Bundo M, Miyashita T, Okamura-Oho Y, Tadokoro K, Tokunaga K, Yamada M | title = Protein binding of a DRPLA family through arginine-glutamic acid dipeptide repeats is enhanced by extended polyglutamine | journal = Hum Mol Genet | volume = 9 | issue = 9 | pages = 1433–42 | year = 2000 | month = Aug | pmid = 10814707 | pmc = | doi =10.1093/hmg/9.9.1433 }}</ref><ref name="pmid10729226">{{cite journal | author = Amler LC, Bauer A, Corvi R, Dihlmann S, Praml C, Cavenee WK, Schwab M, Hampton GM | title = Identification and characterization of novel genes located at the t(1;15)(p36.2;q24) translocation breakpoint in the neuroblastoma cell line NGP | journal = Genomics | volume = 64 | issue = 2 | pages = 195–202 | year = 2000 | month = May | pmid = 10729226 | pmc = | doi = 10.1006/geno.1999.6097 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: RERE arginine-glutamic acid dipeptide (RE) repeats| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=473| accessdate = }}</ref>

<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text = This gene encodes a member of the atrophin family of arginine-glutamic acid (RE) dipeptide repeat-containing proteins. The encoded protein co-localizes with a transcription factor in the nucleus, and its overexpression triggers apoptosis. A similar protein in mouse associates with histone deacetylase and is thought to function as a transcriptional co-repressor during embryonic development. Recent reports also indicate that RERE and its Drosophila homolog associate with histone methyltransferases in regulating gene expression. Multiple transcript variants encoding different isoforms have been found for this gene.<ref name="entrez" />
}}

==Interactions==
RERE has been shown to [[Protein-protein_interaction|interact]] with [[ATN1]].<ref name=pmid10814707>{{cite journal |last=Yanagisawa |first=H |authorlink= |coauthors=Bundo M, Miyashita T, Okamura-Oho Y, Tadokoro K, Tokunaga K, Yamada M |year=[[2000]]|month=May. |title=Protein binding of a DRPLA family through arginine-glutamic acid dipeptide repeats is enhanced by extended polyglutamine |journal=Hum. Mol. Genet. |volume=9 |issue=9 |pages=1433–42 |publisher= |location = ENGLAND| issn = 0964-6906| pmid = 10814707 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |doi=10.1093/hmg/9.9.1433 }}</ref>

==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
*{{cite journal | author=Wang, L, Rajan, H, Pitman, JL, McKeown, M and Tsai, CC |title=Histone deacetylase-associating Atrophin proteins are nuclear receptor corepressors |journal=Genes & Development |volume=20 |issue= 5|pages= 525–30 |year= 2006 |pmid= 16481466|doi= 10.1101/gad.1393506 | pmc=1410805 }}
*{{cite journal | author=Wang, L, Charroux, B, Kerridge, S and Tsai, CC |title=Atrophin recruits HDAC1/2 and G9a to modify histone H3K9 and to determine cell fates |journal=EMBO Reports |volume=9 |issue= 6 |pages= 555–62 |year= 2008 |pmid= 18451879|doi= 10.1038/embor.2008.67 | pmc=2427389 }}
{{PBB_Further_reading
| citations =
*{{cite journal | author=Seki N |title=Characterization of cDNA clones in size-fractionated cDNA libraries from human brain |journal=DNA Res. |volume=4 |issue= 5 |pages= 345–9 |year= 1998 |pmid= 9455484 |doi=10.1093/dnares/4.5.345 | author-separator=, | author2=Ohira M | author3=Nagase T | display-authors=3 | last4=Ishikawa | first4=K | last5=Miyajima | first5=N | last6=Nakajima | first6=D | last7=Nomura | first7=N | last8=Ohara | first8=O }}
*{{cite journal | author=Waerner T |title=Human RERE is localized to nuclear promyelocytic leukemia oncogenic domains and enhances apoptosis |journal=Cell Growth Differ. |volume=12 |issue= 4 |pages= 201–10 |year= 2003 |pmid= 11331249 |doi= | author-separator=, | author2=Gardellin P | author3=Pfizenmaier K | display-authors=3 | last4=Weith | first4=A | last5=Kraut | first5=N }}
*{{cite journal | author=Yi J |title=Members of the Zyxin family of LIM proteins interact with members of the p130Cas family of signal transducers |journal=J. Biol. Chem. |volume=277 |issue= 11 |pages= 9580–9 |year= 2002 |pmid= 11782456 |doi= 10.1074/jbc.M106922200 | author-separator=, | author2=Kloeker S | author3=Jensen CC | display-authors=3 | last4=Bockholt | first4=S | last5=Honda | first5=H | last6=Hirai | first6=H | last7=Beckerle | first7=MC }}
*{{cite journal | author=Wistow G |title=Expressed sequence tag analysis of adult human lens for the NEIBank Project: over 2000 non-redundant transcripts, novel genes and splice variants |journal=Mol. Vis. |volume=8 |issue= |pages= 171–84 |year= 2002 |pmid= 12107413 |doi= | author-separator=, | author2=Bernstein SL | author3=Wyatt MK | display-authors=3 | last4=Behal | first4=A | last5=Touchman | first5=JW | last6=Bouffard | first6=G | last7=Smith | first7=D | last8=Peterson | first8=K }}
*{{cite journal | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 | author-separator=, | author2=Feingold EA | author3=Grouse LH | display-authors=3 | last4=Derge | first4=JG | last5=Klausner | first5=RD | last6=Collins | first6=FS | last7=Wagner | first7=L | last8=Shenmen | first8=CM | last9=Schuler | first9=GD }}
*{{cite journal | author=Tomarev SI |title=Gene expression profile of the human trabecular meshwork: NEIBank sequence tag analysis |journal=Invest. Ophthalmol. Vis. Sci. |volume=44 |issue= 6 |pages= 2588–96 |year= 2003 |pmid= 12766061 |doi=10.1167/iovs.02-1099 | author-separator=, | author2=Wistow G | author3=Raymond V | display-authors=3 | last4=Dubois | first4=S | last5=Malyukova | first5=I }}
*{{cite journal | author=Zoltewicz JS, Stewart NJ, Leung R, Peterson AS |title=Atrophin 2 recruits histone deacetylase and is required for the function of multiple signaling centers during mouse embryogenesis |journal=Development |volume=131 |issue= 1 |pages= 3–14 |year= 2004 |pmid= 14645126 |doi= 10.1242/dev.00908 }}
*{{cite journal | author=Ota T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 | author-separator=, | author2=Suzuki Y | author3=Nishikawa T | display-authors=3 | last4=Otsuki | first4=Tetsuji | last5=Sugiyama | first5=Tomoyasu | last6=Irie | first6=Ryotaro | last7=Wakamatsu | first7=Ai | last8=Hayashi | first8=Koji | last9=Sato | first9=Hiroyuki }}
*{{cite journal | author=Beausoleil SA |title=Large-scale characterization of HeLa cell nuclear phosphoproteins |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130–5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101 | pmc=514446 | author-separator=, | author2=Jedrychowski M | author3=Schwartz D | display-authors=3 | last4=Elias | first4=JE | last5=Villén | first5=J | last6=Li | first6=J | last7=Cohn | first7=MA | last8=Cantley | first8=LC | last9=Gygi | first9=SP }}
*{{cite journal | author=Otsuki T |title=Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries |journal=DNA Res. |volume=12 |issue= 2 |pages= 117–26 |year= 2007 |pmid= 16303743 |doi= 10.1093/dnares/12.2.117 | author-separator=, | author2=Ota T | author3=Nishikawa T | display-authors=3 | last4=Hayashi | first4=K | last5=Suzuki | first5=Y | last6=Yamamoto | first6=J | last7=Wakamatsu | first7=A | last8=Kimura | first8=K | last9=Sakamoto | first9=K }}
*{{cite journal | author=Kimura K |title=Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406 | pmc=1356129 | author-separator=, | author2=Wakamatsu A | author3=Suzuki Y | display-authors=3 | last4=Ota | first4=T | last5=Nishikawa | first5=T | last6=Yamashita | first6=R | last7=Yamamoto | first7=J | last8=Sekine | first8=M | last9=Tsuritani | first9=K }}
*{{cite journal | author=Gregory SG |title=The DNA sequence and biological annotation of human chromosome 1 |journal=Nature |volume=441 |issue= 7091 |pages= 315–21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727 | author-separator=, | author2=Barlow KF | author3=McLay KE | display-authors=3 | last4=Kaul | first4=R. | last5=Swarbreck | first5=D. | last6=Dunham | first6=A. | last7=Scott | first7=C. E. | last8=Howe | first8=K. L. | last9=Woodfine | first9=K. }}
*{{cite journal | author=Lim J |title=A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration |journal=Cell |volume=125 |issue= 4 |pages= 801–14 |year= 2006 |pmid= 16713569 |doi= 10.1016/j.cell.2006.03.032 | author-separator=, | author2=Hao T | author3=Shaw C | display-authors=3 | last4=Patel | first4=Akash J. | last5=Szabó | first5=Gábor | last6=Rual | first6=Jean-François | last7=Fisk | first7=C. Joseph | last8=Li | first8=Ning | last9=Smolyar | first9=Alex }}
*{{cite journal | author=Olsen JV |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 | author-separator=, | author2=Blagoev B | author3=Gnad F | display-authors=3 | last4=Macek | first4=Boris | last5=Kumar | first5=Chanchal | last6=Mortensen | first6=Peter | last7=Mann | first7=Matthias }}
}}
{{refend}}

{{gene-1-stub}}

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Revision as of 22:25, 6 December 2011

Rere, is french for "Kill the Jews" In 1940, Hitler, spoke to a crowd of french citizens, and at the end of his speech, he yelled "RERE"

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