Regional Centre of Advanced Technologies and Materials

The Regional Centre of Advanced Technologies and Materials (RCPTM) is a scientific and research centre connected to the Faculty of Science, Palacký University, Olomouc. Its chief objective is to produce superlative research and to transfer high-tech products and technologies to medical, industrial and environmental practice with a pronounced emphasis on connecting the Centre to international networks and collaborations. The center was established on 1 October 2010, and since October 2013 is housed in a high-tech new building in Palacky University campus at Šlechtitelů street.

RCPTM is mainly engaged in chemical, material and optical research. Priority areas of research include nanoparticles of metal oxides for catalytic, magnetic and biomedical applications, carbon nanostructures based on graphene and quantum dots, metal nanoparticles for antimicrobial treatment and technology of water purification, medical, computer and coordination chemistry, photonics and development of instrumental techniques for applications in optics and analytical chemistry.

The center is linked with research institutes Palacky University, supports the creation of new companies focused on sophisticated technology.

In 2016 formed the basis for personnel RCPTM approximately 100 member research team consisting of more than 20 percent of foreign experts. General Director of the Centre is Prof. RNDr. Radek Zboril, Ph.D.

Center Research Divisions

The structure of the seven research divisions is in accordance with the seven research programmes of the Centre.

• Magnetic nanostructures
• Carbon Nanostructures, Biomolecules and Simulations
• Biologically Active Complexes and Molecular Magnets
• Optical and Photonic Technologies
• Nanomaterials in biomedicine
• Nanotechnology in Analytical Chemistry
• Environmental Nanotechnologies

Grant activities

Over the period 2010-2013, the staff of the Centre succeeded in a total of 55 submitted projects, whose grants for RCPTM amounted to over CZK 520 mil.

Mezi nejvýznamnější patří:

• ERC-Consolidator grant: Two-Dimensional Chemistry towards New Graphene Derivatives
• Nanobiowat, Alterbio- (Centra kompetence,Technologická agentura České republiky)
• NanoRem, EcoThermo- (7. EU Framework Programme)

The center is also involved in prestigious international collaborations type Pierre Auger Observatory, Cherenkov Telescope Array, or CERN-ATLAS.

Scientific Results

Important Publications

• V. Georgakilas, M. Otyepka, A.B. Bourlinos, V. Chandra, N. Kim, K.C. Kemp, P. Hobza, R. Zboril, K.S. Kim: „

Functionalization of Graphene: Covalent and Non-Covalent Approaches, Derivatives and Applications“, Chem. Rev. 112, 6156-6214 (2012).

• P.Hobza: „Calculations on Noncovalent Interactions and Databases of Benchmark Interaction energie“, Acc. Chem. Res. 45, 663–672 (2012).
• K.E. Riley, P. Hobza: „On the Importance and Origin of Aromatic Interactions in Chemistry and Biodisciplines“, Acc. Chem. Res. 46, 927-936 (2013).
• P. Lazar, S. Zhang, K. Safarova, Q. Li, J.P. Froning, J. Granatier, P. Hobza, R. Zboril, F. Besenbacher, M. Dong, M. Otyepka: „Quantification of the Interaction Forces between Metals and Graphene by Quantum Chemical Calculations and Dynamic Force Measurements under Ambient Conditions“, ACS Nano 7, 1646-1651 (2013).
• F. Karlicky, K.K.R. Datta, M. Otyepka, R. Zboril: „Halogenated Graphenes: Rapidly Growing Family of Graphene Derivatives“, ACS Nano 7, 6434-6464 (2013).
• T. Zeleny, M. Ruckenbauer, A.J.A. Aquino, T. Muller, F. Lankas, T. Drsata, W.L. Hase, D. Nachtigallova, H. Lischka: „Strikingly Different Effects of Hydrogen Bonding on the Photodynamics of Individual Nucleobases in DNA: Comparison of Guanine and Cytosine“, J. Am. Chem. Soc. 134, 13662-13669 (2012).
• P. Lazar, F. Karlicky, P. Jurecka, M. Kocman, E. Otyepkova, K. Safarova, M. Otyepka: „Adsorption of Small Organic Molecules on Graphene“, J. Am. Chem. Soc. 135, 6372-6377 (2013).
• K. Berka, O. Hanak, D. Sehnal, P. Banas, V. Navratilova, D. Jaiswal, C.M. Ionescu, R. Svobodova-Varekova, J. Koca, M. Otyepka: „MOLEonline 2.0: Interactive Web-based Analysis of Biomacromolecular Channels“, Nuc. Acids. Res. 40, W222 (2012).
• L. Machala, J. Tucek, R. Zboril: „Polymorphous Transformations of Nanometric Iron(III) Oxide: A Review“, Chem. Mater. 23, 3255-3272 (2011).
• A. B. Bourlinos, R. Zboril, J. Petr, A. Bakandritsos, M. Krysmann, E. P. Giannelis: „Luminescent Surface Quaternized Carbon Dots“, Chem. Mater. 24, 6−8 (2012).

Patents

• Gold complexes with ω-substituted derivatives of 6-alkyloxy-9-deazapurines and phosphane derivatives and use of these complexes for the preparation of drugs for the therapy of inflammatory and tumour diseases (CZ 305624 B6 12/2015).
• Gold complexes with hypoxanthine derivatives and phosphane derivatives and their use for preparation of drugs in anti-inflammatory and antitumour therapy (CZ 305585 B6, 11/2015)
• Dichlorido complexes of platinum with kinetin derivatives, method of their preparation and use of these complexes as drugs in anticancer treatment (CZ 305411 B6, 08/2015)
• Platinum dijodido-complexes and their use for preparation of drugs for the treatment of tumour diseases (CZ 305374 B6, 07/2015)
• Dichlorido complexes of platinum with 7-azaindole halogeno-derivatives for use in the treatment of tumour diseases (EP2636410 B1, 04/2015)
• Salophen complexes of iron with heterocyclic N-donor ligands, method of their preparation and use as drugs in anticancer treatment (CZ 304883 B6, 11/2014)
• Process for preparing aqueous dispersions of metal nanoparticles (CZ 304160)
• Method of activation of aqueous dispersions of silver nanoparticles for surface-enhanced Raman spectroscopy (CZ 304231)
• The method of synthesis of the iron nanopowder with the protective oxidic coat from natural and synthetic nanopowdered iron oxides and oxyhydroxides (EP2164656)
• Universal approach for immobilization of silver nanoparticles onto solid substrates using polyethylenimine with branch structure as adhesive layer and reducing agent. (CZ2012000068)
• Use of copper complexes containing 2-phenyl-3-hydroxyquinolin-4(1H)-one and 1,10-phenanthroline derivatives for preparing medicaments intended for the treatment of tumor diseases (CZ 304045).
• Complexes of gold with N6-benzyladenine derivatives and phosphine derivatives, method of their preparation and application of these complexes as drugs in anti-inflammatory therapy. (CZ 303649).
• Utilization of the dichlorido complexes of platinum with 7-azaindole halogeno-derivatives for the preparation of drugs for the treatment of tumour diseases. (CZ 303560)
• Dichlorido complexes of platinum with 7-azaindole halogeno-derivatives and application of these complexes as drugs in antitumor therapy. (CZ 303417).
• Complexes of copper with 2-phenyl-3-hydroxychinolin-4(1H)-one derivatives, method of their preparation and application of these complexes as drugs in antitumor therapy. (CZ 303009).
• Platinum oxalate-complexes with N6-benzyladenine derivatives, process of their preparation and use of such complexes as medicaments in antitumor therapy. (CZ 302623).
• Platinum cyclobutane-1,1-dicarboxylato complexes with N6-benzyladenine derivatives, synthesis and their use in anticancer therapy. (CZ 302618).
• Immobilization method of silver nanoparticles to solid substrates. (CZ 303502).
• Deposition method of metallic nanoparticles onto substrate surface. (CZ 303566).
• Method of contactless detection of moving object absolute position by making use of coherence granularity phenomenon and apparatus for making the same. (CZ 304207).
• Iron oxide nanoparticles with enhanced T2 relaxation indices for magnetic resonance representation and process for preparing thereof. (Application no. 2012-458)