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Vacuolar fusion protein Mon1

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(Redirected from SAND protein)

SAND protein family, first described in Saccharomyces cerevisiae (but also in the animals Fugu rubripes, Caenorhabditis elegans, Drosophila melanogaster and Homo sapiens and in the plant Arabidopsis thaliana using comparative genomics[1]), is membrane protein related with vesicle traffic: vacuole fusion in yeasts and lysosome one motility in mammals and other taxa.[1] In humans has been described an interaction with HSV-1, a virus which produces Herpes simplex.[2]

See also

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References

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  1. ^ a b Cottage A, Mullan L, Portela MB, et al. (2004). "Molecular characterisation of the SAND protein family: a study based on comparative genomics, structural bioinformatics and phylogeny" (PDF). Cell. Mol. Biol. Lett. 9 (4A): 739–53. PMID 15647795.
  2. ^ Dong S, Dong C, Liu L, et al. (2003). "Identification of a novel human sand family protein in human fibroblasts induced by herpes simplex virus 1 binding" (PDF). Acta Virol. 47 (1): 27–32. PMID 12828340.