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TREE-PUZZLE is a computer program used to construct phylogenetic trees from sequence data by maximum likelihood analysis. Branch lengths can be calculated with and without the molecular clock hypothesis.

The program's successor is IQ-TREE.[1]

See also[edit]


  1. ^ Nguyen, Lam-Tung; Schmidt, Heiko A.; von Haeseler, Arndt; Minh, Bui Quang (2015). "IQ-TREE: A Fast and Effective Stochastic Algorithm for Estimating Maximum-Likelihood Phylogenies". Molecular Biology and Evolution. 32 (W1): W268–W274. doi:10.1093/molbev/msu300. PMC 4271533Freely accessible. 

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