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Turnip crinkle virus (TCV) repressor of minus strand synthesis H5

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Turnip crinkle virus (TCV) repressor of minus strand synthesis H5
Identifiers
SymbolTCV_H5
RfamRF00500
Other data
RNA type Cis-reg
Domain(s)Viruses
SOSO:0000233
PDB structuresPDBe

The TCV hairpin 5 (H5) is an RNA element found in the turnip crinkle virus. This RNA element is composed of a stem-loop that contains a large symmetrical internal loop (LSL). H5 can repress minus-strand synthesis when the 3' side of the LSL pairs with the 4 bases at the 3'-terminus of the RNA(GCCC-OH).[1][2]

See also

References

  1. ^ McCormack, JC; Simon AE (2004). "Biased hypermutagenesis associated with mutations in an untranslated hairpin of an RNA virus". J Virol. 78 (14): 7813–7817. doi:10.1128/JVI.78.14.7813-7817.2004. PMC 434097. PMID 15220455.
  2. ^ Zhang, G; Zhang J; Simon AE (2004). "Repression and derepression of minus-strand synthesis in a plus-strand RNA virus replicon". J Virol. 78 (14): 7619–7633. doi:10.1128/JVI.78.14.7619-7633.2004. PMC 434078. PMID 15220437.