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Ubiquilin 4

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Template:PBB Ubiquilin 4 is a protein in humans that is encoded by the UBQLN4 gene.[1][2][3] Ubiquilin 4 regulates proteasomal protein degradation.[4]

Similarity to Other Proteins

Human UBQLN4 shares a high degree of similarity with related ubiquilins including UBQLN1 and UBQLN2.[5]

References

  1. ^ "Entrez Gene: Ubiquilin 4". Retrieved 2013-06-27.
  2. ^ Davidson JD, Riley B, Burright EN, Duvick LA, Zoghbi HY, Orr HT (September 2000). "Identification and characterization of an ataxin-1-interacting protein: A1Up, a ubiquitin-like nuclear protein". Hum. Mol. Genet. 9 (15): 2305–12. doi:10.1093/oxfordjournals.hmg.a018922. PMID 11001934.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  3. ^ Matsuda M, Koide T, Yorihuzi T, Hosokawa N, Nagata K (January 2001). "Molecular cloning of a novel ubiquitin-like protein, UBIN, that binds to ER targeting signal sequences". Biochem. Biophys. Res. Commun. 280 (2): 535–40. doi:10.1006/bbrc.2000.4149. PMID 11162551.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  4. ^ Riley BE, Xu Y, Zoghbi HY, Orr HT (October 2004). "The effects of the polyglutamine repeat protein ataxin-1 on the UbL-UBA protein A1Up". J. Biol. Chem. 279 (40): 42290–301. doi:10.1074/jbc.M406284200. PMID 15280365.{{cite journal}}: CS1 maint: multiple names: authors list (link) CS1 maint: unflagged free DOI (link)
  5. ^ Marín I (March 2014). "The ubiquilin gene family: evolutionary patterns and functional insights". BMC Evol Biol. 14: 63. doi:10.1186/1471-2148-14-63. PMID 24674348.{{cite journal}}: CS1 maint: unflagged free DOI (link)