User:Mr. Ibrahem/Factor IX concentrate

From Wikipedia, the free encyclopedia
< User:Mr. Ibrahem

This is the current revision of this page, as edited by Mr. Ibrahem (talk | contribs) at 00:40, 7 March 2024 (from https://mdwiki.org/wiki/Factor_IX_concentrate). The present address (URL) is a permanent link to this version.

(diff) ← Previous revision | Latest revision (diff) | Newer revision → (diff)
Not to be confused with Coagulation factor IX complex or Recombinant factor IX.
Mr. Ibrahem/Factor IX concentrate
Clinical data
Trade namesHaemonine, Benefix, others
Other namesFactor IX fraction[1]

Factor IX concentrate, sold under the brand names Haemonine and Benefix among others, is a medication used to treat haemophilia B.[2] Specifically they are used to treat and prevent bleeding.[2] They are given by injection into a vein.[2]

Common side effects include anxiety, shortness of breath, allergic reactions, nausea, and back pain.[1] Other side effects may include angioedema and chest pain.[1] Antibodies that block its ability to work may also develop.[2] It should not be used in disseminated intravascular coagulation.[1] They are manufactured versions of factor IX made from human plasma or by recombinant methods.[2] Risks from versions made from plasma include infection.[2]

Factor IX concentrate became available in the late 1960s, while recombinant versions were approved in 1997.[2][3] It is on the World Health Organization's List of Essential Medicines.[4] In the United Kingdom 1,000 units of the recombinant or plasma derived versions costs the NHS about £600 as of 2023.[5] Longer acting versions are also available.[2]

References[edit]

  1. ^ a b c d e "Factor IX fraction, dried [Specialist drug]". BNF. Archived from the original on 16 September 2023. Retrieved 13 September 2023.
  2. ^ a b c d e f g h i j Konkle, Barbara A (9 February 2023). Hemophilia B. GeneReviews. Archived from the original on 20 October 2019. Retrieved 13 September 2023.
  3. ^ "Hemophilia: From Plasma to Recombinant Factors". 2008. Archived from the original on 29 May 2023. Retrieved 13 September 2023.
  4. ^ World Health Organization (2023). The selection and use of essential medicines 2023: web annex A: World Health Organization model list of essential medicines: 23rd list (2023). Geneva: World Health Organization. hdl:10665/371090. WHO/MHP/HPS/EML/2023.02.
  5. ^ "Factor IX fraction, dried [Specialist drug] Medicinal forms". BNF. Archived from the original on 13 September 2023. Retrieved 13 September 2023.
Retrieved from "https://en.wikipedia.org/w/index.php?title=User:Mr._Ibrahem/Factor_IX_concentrate&oldid=1212273948"