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Wohl–Aue reaction

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The Wohl–Aue reaction is an organic reaction between an aromatic nitro compound and an aniline to form a phenazine in presence of an alkali base.[1][2] An example is the reaction between nitrobenzene and aniline:

The Wohl-Aue reaction
The Wohl-Aue reaction

The reaction is named after Alfred Wohl and W. Aue.

References

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  1. ^ Alfred Wohl and W. Aue (1901). "Über die Einwirkung von Nitrobenzol auf Anilin bei Gegenwart von Alkali". Chemische Berichte. 34 (2): 2442–2450. doi:10.1002/cber.190103402183. hdl:2027/uc1.b2652529.
  2. ^ Irwin J. Pachter and Milton C. Kloetzel (1951). "The Wohl-Aue Reaction. I. Structure of Benzo [a] phenazine Oxides and Syntheses of 1,6-Dimethoxyphenazine and 1,6-Dichlorophenazine". J. Am. Chem. Soc. 73 (10): 4958–4961. doi:10.1021/ja01154a144.