Zieve's syndrome is an acute metabolic condition that can occur during withdrawal from prolonged alcohol abuse. It is defined by hemolytic anemia (with spur cells and acanthocytes), hyperlipoproteinaemia (excessive blood lipoprotein), jaundice, and abdominal pain. The underlying cause is liver delipidization. This is distinct from alcoholic hepatitis which, however, may present simultaneously or develop later.
^Mehta, AB; N McIntyre (2004). Oxford Textbook of Clinical Hepatology. Oxford University Press. pp. 1786–1787. ISBN0-19-262515-2.
^Zieve, L (March 1958). "Jaundice, hyperlipemia and hemolytic anemia: a heretofore unrecognized syndrome associated with alcoholic fatty liver and cirrhosis". Annals of Internal Medicine48 (3): 471–476. doi:10.7326/0003-4819-48-3-471. PMID13521581.