Hydroxycarteolol

Hydroxycarteolol
Clinical data
Other names	8-Hydroxycarteolol
ATC code	None;
Identifiers
	IUPAC name 8-Hydroxy-5-{2-hydroxy-3-[(2-methyl-2-propanyl)amino]propoxy}-3,4-dihydro-2(1H)-quinolinone;
CAS Number	59826-22-1;
PubChem CID	124688;
ChemSpider	111020;
ChEBI	CHEBI:192312;
CompTox Dashboard (EPA)	DTXSID50975219 ;
Chemical and physical data
Formula	C16H24N2O4
Molar mass	308.378 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C2Nc1c(O)ccc(OCC(O)CNC(C)(C)C)c1CC2;
	InChI InChI=1S/C16H24N2O4/c1-16(2,3)17-8-10(19)9-22-13-6-5-12(20)15-11(13)4-7-14(21)18-15/h5-6,10,17,19-20H,4,7-9H2,1-3H3,(H,18,21); Key:TVZJLAKRXHGVOK-UHFFFAOYSA-N;

Hydroxycarteolol is a beta blocker and metabolite of carteolol.^[1]^[2]

References

^ Igarashi H, Katsuta Y, Sawa K, Nakazato Y, Kawasaki T (Apr 1990). "A comparison of the opacifying effects of carteolol.HCl and 8-hydroxycarteolol.HCl in the isolated porcine cornea". Fundam Appl Toxicol. 14 (3): 554–559. doi:10.1093/toxsci/14.3.554. PMID 2340982.
^ Jasper JR, Michel MC, Insel PA (1990). "The beta-adrenoceptor antagonist carteolol and its metabolite 8-hydroxycarteolol have different intrinsic sympathomimetic activities". Br J Clin Pharmacol. 30 (Suppl 1): 109S–111S. doi:10.1111/j.1365-2125.1990.tb05477.x. PMC 1368107. PMID 2176514.

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