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Quinolacetic acid

From Wikipedia, the free encyclopedia
Quinolacetic acid
Names
Preferred IUPAC name
(1-Hydroxy-4-oxocyclohexa-2,5-dien-1-yl)acetic acid
Identifiers
3D model (JSmol)
ChemSpider
UNII
  • InChI=1S/C8H8O4/c9-6-1-3-8(12,4-2-6)5-7(10)11/h1-4,12H,5H2,(H,10,11)
    Key: RFJUCKOEXRTZPN-UHFFFAOYSA-N
  • InChI=1/C8H8O4/c9-6-1-3-8(12,4-2-6)5-7(10)11/h1-4,12H,5H2,(H,10,11)
    Key: RFJUCKOEXRTZPN-UHFFFAOYAA
  • O=C\1\C=C/C(O)(/C=C/1)CC(=O)O
Properties
C8H8O4
Molar mass 168.148 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Quinolacetic acid is a chemical compound associated with the metabolic disorder hawkinsinuria.[1] It is the byproduct of a partially defective enzyme, 4-hydroxyphenylpyruvate dioxygenase.[1]

References

[edit]
  1. ^ a b Hocart, Charles H.; Halpern, Berthold; Hick, Larry A.; Wong, Choon O.; Hammond, Judith W.; Wilcken, Bridget (1983). "Hawkinsinuria — identification of quinolacetic acid and pyroglutamic acid during an acidotic phase". Journal of Chromatography B: Biomedical Sciences and Applications. 275 (2): 237–243. doi:10.1016/s0378-4347(00)84371-6. PMID 6619234.